Mohanad Mossalam, Ph.D.

Affiliations: 
2012 Pharmaceutics and Pharmaceutical Chemistry University of Utah, Salt Lake City, UT 
Area:
Molecular Biology, Polymer Chemistry, Oncology
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"Mohanad Mossalam"
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Parents

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Carol S. Lim grad student 2012 University of Utah
 (Subcellular targeting: Delivering therapeutics to the next level.)
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Publications

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Matissek KJ, Okal A, Mossalam M, et al. (2014) Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax. Pharmaceutical Research. 31: 2503-15
Matissek KJ, Mossalam M, Okal A, et al. (2013) The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria. Molecular Pharmaceutics. 10: 3592-602
Okal A, Mossalam M, Matissek KJ, et al. (2013) A chimeric p53 evades mutant p53 transdominant inhibition in cancer cells. Molecular Pharmaceutics. 10: 3922-33
Reaz S, Mossalam M, Okal A, et al. (2013) A single mutant, A276S of p53, turns the switch to apoptosis. Molecular Pharmaceutics. 10: 1350-9
Davis JR, Mossalam M, Lim CS. (2013) Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2. Molecular Pharmaceutics. 10: 1340-9
Mossalam M, Soto J, Lim CS, et al. (2013) Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress. Plos One. 8: e53272
Matissek KJ, Mossalam M, Okal A, et al. (2013) Abstract 791: Targeting small domains of p53 to mitochondrial Bcl-XL for cancer therapy. Cancer Research. 73: 791-791
Okal A, Mossalam M, Matissek KJ, et al. (2013) Abstract 790: An alternative tetramerization domain of p53 for exclusive homo-oligomerization and potent tumor suppression. Cancer Research. 73: 790-790
Constance JE, Woessner DW, Matissek KJ, et al. (2012) Enhanced and selective killing of chronic myelogenous leukemia cells with an engineered BCR-ABL binding protein and imatinib. Molecular Pharmaceutics. 9: 3318-29
Davis JR, Mossalam M, Lim CS. (2012) Utilizing the estrogen receptor ligand-binding domain for controlled protein translocation to the insoluble fraction. Pharmaceutical Research. 29: 3455-63
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