Nathan A. Bruender, Ph.D.
Affiliations: | 2012 | Biochemistry-ALS | University of Wisconsin, Madison, Madison, WI |
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Parents
Sign in to add mentor| Hazel Marguerite Holden | grad student | 2012 | UW Madison | |
| (A structural and functional investigation of enzymes involved in the biosynthesis of D-tetronitrose.) | ||||
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Publications
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| Grell TAJ, Bell BN, Nguyen C, et al. (2018) Crystal structure of AdoMet radical enzyme 7-carboxy-7-deazaguanine synthase from Escherichia coli suggests how modifications near [4Fe-4S] cluster engender flavodoxin specificity. Protein Science : a Publication of the Protein Society |
| Grell TAJ, Kincannon WM, Bruender NA, et al. (2018) Structural and spectroscopic analyses of the sporulation killing factor biosynthetic enzyme SkfB, a bacterial AdoMet radical sactisynthase. The Journal of Biological Chemistry |
| Lewis JK, Bruender NA, Bandarian V. (2018) QueE: A Radical SAM Enzyme Involved in the Biosynthesis of 7-Deazapurine Containing Natural Products. Methods in Enzymology. 606: 95-118 |
| Kincannon W, Bruender NA, Bandarian V. (2018) A Radical Clock Probe Uncouples H-atom Abstraction from Thi-oether Crosslink Formation by the Radical SAM Enzyme SkfB. Biochemistry |
| Wilcoxen J, Bruender NA, Bandarian V, et al. (2018) A Radical Intermediate in Bacillus subtilis QueE During Turnover With the Substrate Analog 6-Carboxypterin. Journal of the American Chemical Society |
| Bruender NA, Bandarian V. (2017) The creatininase homolog MftE from Mycobacterium smegmatis catalyzes a peptide cleavage reaction in the biosynthesis of a novel RiPP. The Journal of Biological Chemistry |
| Bruender NA, Grell TA, Dowling DP, et al. (2017) 7-Carboxy-7-deazaguanine synthase - A radical S-adenosyl-L-methionine enzyme with polar tendencies. Journal of the American Chemical Society |
| Bruender NA, Bandarian V. (2016) SkfB abstracts a hydrogen atom from Cα on SkfA to initiate thioether crosslink formation. Biochemistry |
| Bruender NA, Bandarian V. (2016) The radical S-adenosyl-L-methionine enzyme MftC catalyzes an oxidative decarboxylation of the C-terminus of the MftA peptide. Biochemistry |
| Bruender NA, Wilcoxen J, Britt RD, et al. (2016) Biochemical and spectroscopic characterization of a radical SAM enzyme involved in the formation of a peptide thioether crosslink. Biochemistry |