Charles A. Testa, Ph.D.

Affiliations: 
2002 University of Utah, Salt Lake City, UT 
Area:
Biochemistry, Molecular Biology
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"Charles Testa"
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C. Dale Poulter grad student 2002 University of Utah
 (A synthetic mevalonate operon for studying the methyl erythritol phosphate pathway.)
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Publications

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Fox DT, Schmidt EN, Tian H, et al. (2014) Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. Plos One. 9: e95271
Madan D, Ferguson CG, Lee WY, et al. (2013) Non-invasive imaging of tumors by monitoring autotaxin activity using an enzyme-activated near-infrared fluorogenic substrate. Plos One. 8: e79065
Testa CA, Johnson LJ. (2012) A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. Antimicrobial Agents and Chemotherapy. 56: 4906-13
Testa CA, Lherbet C, Pojer F, et al. (2006) Cloning and expression of IspDF from Mesorhizobium loti. Characterization of a bifunctional protein that catalyzes non-consecutive steps in the methylerythritol phosphate pathway. Biochimica Et Biophysica Acta. 1764: 85-96
Dhiman RK, Schaeffer ML, Bailey AM, et al. (2005) 1-Deoxy-D-xylulose 5-phosphate reductoisomerase (IspC) from Mycobacterium tuberculosis: towards understanding mycobacterial resistance to fosmidomycin. Journal of Bacteriology. 187: 8395-402
Testa CA, Cornish RM, Poulter CD. (2004) The sorbitol phosphotransferase system is responsible for transport of 2-C-methyl-D-erythritol into Salmonella enterica serovar typhimurium. Journal of Bacteriology. 186: 473-80
Testa CA, Brown MJ. (2003) The methylerythritol phosphate pathway and its significance as a novel drug target. Current Pharmaceutical Biotechnology. 4: 248-59
Hahn FM, Eubanks LM, Testa CA, et al. (2001) 1-Deoxy-D-xylulose 5-phosphate synthase, the gene product of open reading frame (ORF) 2816 and ORF 2895 in Rhodobacter capsulatus. Journal of Bacteriology. 183: 1-11
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