Jeffrey D. Rudolf, Ph.D.
Affiliations: | 2007-2013 | Chemistry | University of Utah, Salt Lake City, UT |
| 2013-2018 | Chemistry | The Scripps Research Institute, Scripps Florida | |
| 2018- | Chemistry | University of Florida, Gainesville, Gainesville, FL, United States |
Area:
Natural Products, Biosynthesis, Enzymology, Genome Mining, BioengineeringGoogle:
"Jeffrey D Rudolf"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| C. Dale Poulter | grad student | 2007-2013 | University of Utah | |
| (PhD Thesis: Dimethylallyltyrosine synthase and dimethylallyltryptophan synthase: Promiscuous aromatic prenyltransferases.) | ||||
| Ben Shen | post-doc | 2013-2018 | The Scripps Research Institute, Scripps Florida | |
| (NIH K99 Pathway to Independence Award. Former Arnold O. Beckman Postdocotral Fellow. Projects: Platensimycin and Platencin Biosynthesis, Genome Mining and Natural Products Discovery, Enzymology and Structural Biology) | ||||
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Publications
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| Fluegel LL, Deng MR, Su P, et al. (2024) Development of platensimycin, platencin, and platensilin overproducers by biosynthetic pathway engineering and fermentation medium optimization. Journal of Industrial Microbiology & Biotechnology |
| Wang Z, Yang Q, He J, et al. (2023) Cytochrome P450 Mediated Cyclization in Eunicellane Derived Diterpenoid Biosynthesis. Angewandte Chemie (International Ed. in English). e202312490 |
| Zheng YZ, Cui J, Wang YL, et al. (2022) The Structure-Function Relationship of Human Bleomycin Hydrolase: Mutation of a Cysteine Protease into a Serine Protease. Chembiochem : a European Journal of Chemical Biology. e202200186 |
| Zhu C, Xu B, Adpressa DA, et al. (2021) Discovery and biosynthesis of a structurally dynamic antibacterial diterpenoid. Angewandte Chemie (International Ed. in English) |
| Rudolf JD, Alsup TA, Xu B, et al. (2020) Bacterial terpenome. Natural Product Reports |
| Zhang X, King-Smith E, Dong LB, et al. (2020) Divergent synthesis of complex diterpenes through a hybrid oxidative approach. Science (New York, N.Y.). 369: 799-806 |
| Rudolf JD, Chang CY. (2019) Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases. Natural Product Reports |
| Dong LB, Liu YC, Cepeda AJ, et al. (2019) Characterization and Crystal Structure of a Nonheme Diiron Monooxygenase Involved in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society |
| Su M, Qiu L, Deng Y, et al. (2019) Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models. Molecular Pharmaceutics |
| Dong LB, Zhang X, Shen B, et al. (2019) Cryptic and Stereospecific Hydroxylation, Oxidation, and Reduction in Platensimycin and Platencin Biosynthesis. Journal of the American Chemical Society |