Andrew C. Eliot, Ph.D.

Affiliations: 
2003 University of California, Berkeley, Berkeley, CA 
Area:
Biochemistry
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"Andrew Eliot"
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Jack F. Kirsch grad student 2003 UC Berkeley
 (Identification of determinants of substrate and reaction specificity of 1-aminocyclopropane-1-carboxylate synthase and 7,8-diaminopelargonic acid synthase.)
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Publications

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Schärer MA, Eliot AC, Grütter MG, et al. (2011) Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy. Febs Letters. 585: 111-4
Capitani G, Tschopp M, Eliot AC, et al. (2005) Structure of ACC synthase inactivated by the mechanism-based inhibitor L-vinylglycine. Febs Letters. 579: 2458-62
Eliot AC, Kirsch JF. (2004) Pyridoxal phosphate enzymes: mechanistic, structural, and evolutionary considerations. Annual Review of Biochemistry. 73: 383-415
Sandmark J, Eliot AC, Famm K, et al. (2004) Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. Biochemistry. 43: 1213-22
Ko S, Eliot AC, Kirsch JF. (2004) S-methylmethionine is both a substrate and an inactivator of 1-aminocyclopropane-1-carboxylate synthase. Archives of Biochemistry and Biophysics. 421: 85-90
Eliot AC, Kirsch JF. (2003) Avoiding the road less traveled: how the topology of enzyme-substrate complexes can dictate product selection. Accounts of Chemical Research. 36: 757-65
Capitani G, Eliot AC, Gut H, et al. (2003) Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding. Biochimica Et Biophysica Acta. 1647: 55-60
Eliot AC, Sandmark J, Schneider G, et al. (2002) The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation. Biochemistry. 41: 12582-9
Eliot AC, Kirsch JF. (2002) Modulation of the internal aldimine pK(a)'s of 1-aminocyclopropane-1-carboxylate synthase and aspartate aminotransferase by specific active site residues. Biochemistry. 41: 3836-42
Feng L, Geck MK, Eliot AC, et al. (2000) Aminotransferase activity and bioinformatic analysis of 1-aminocyclopropane-1-carboxylate synthase. Biochemistry. 39: 15242-9
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