Arunkumar Kannan, Ph.D.

Affiliations: 
2011 Chemistry University of Utah, Salt Lake City, UT 
Area:
Biochemistry
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"Arunkumar Kannan"
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Parents

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Cynthia J. Burrows grad student 2011 University of Utah
 (Addressing the off-target effects of small interfering RNA using N2-alkyl-8-oxo-2'-deoxyguanosine switches.)
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Publications

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Fleming AM, Kannan A, Muller JG, et al. (2011) Copper/H2O2-mediated oxidation of 2'-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts. The Journal of Organic Chemistry. 76: 7953-63
Peacock H, Kannan A, Beal PA, et al. (2011) Chemical modification of siRNA bases to probe and enhance RNA interference Journal of Organic Chemistry. 76: 7295-7300
Kannan A, Fostvedt E, Beal PA, et al. (2011) 8-oxoguanosine switches modulate the activity of alkylated siRNAs by controlling steric effects in the major versus minor grooves Journal of the American Chemical Society. 133: 6343-6351
Kannan A, Burrows CJ. (2011) Synthesis of N 2-Alkyl-8-oxo-7,8-dihydro-2′-deoxyguanosine derivatives and effects of these modifications on RNA duplex stability Journal of Organic Chemistry. 76: 720-723
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