Katharina Schlacher, Ph.D.

Affiliations: 
2006 University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology
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"Katharina Schlacher"
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Parents

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Myron Goodman grad student 2006 USC
 (The mechanism of damage-induced mutations in Escherichia coli.)
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Publications

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Ye Z, Xu S, Shi Y, et al. (2024) GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer. Nature Communications. 15: 2132
Longo MA, Roy S, Chen Y, et al. (2023) RAD51C-XRCC3 structure and cancer patient mutations define DNA replication roles. Nature Communications. 14: 4445
Lozen M, Chen Y, Boisvert RA, et al. (2023) Mitochondrial Replication Assay (MIRA) for Efficient in situ Quantification of Nascent mtDNA and Protein Interactions with Nascent mtDNA (mitoSIRF). Bio-Protocol. 13: e4680
Luzwick JW, Dombi E, Boisvert RA, et al. (2021) MRE11-dependent instability in mitochondrial DNA fork protection activates a cGAS immune signaling pathway. Science Advances. 7: eabf9441
Hambarde S, Tsai CL, Pandita RK, et al. (2021) EXO5-DNA structure and BLM interactions direct DNA resection critical for ATR-dependent replication restart. Molecular Cell
Msaouel P, Malouf GG, Su X, et al. (2020) Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell
Roy S, Schlacher K. (2019) SIRF: A Single-cell Assay for Protein Interaction with Nascent DNA Replication Forks. Bio-Protocol. 9: e3377
Lazarchuk P, Roy S, Schlacher K, et al. (2019) Detection and Quantitation of Acetylated Histones on Replicating DNA Using In Situ Proximity Ligation Assay and Click-It Chemistry. Methods in Molecular Biology (Clifton, N.J.). 1983: 29-45
Ma S, Pradeep S, Villar-Prados A, et al. (2019) GnRH-R targeted lytic peptide sensitizes BRCA wild-type ovarian cancer to PARP inhibition. Molecular Cancer Therapeutics
Schlacher K. (2019) Sense and sensibility: ATM oxygen stress signaling manages brain cell energetics. The Journal of Cell Biology
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