Huay-Keng Loke, Ph.D.

2001 Texas A & M University, College Station, TX, United States 
Biochemistry, Inorganic Chemistry
"Huay-Keng Loke"
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Paul A. Lindahl grad student 2001 Texas A & M
 (Biosynthesis of acetyl -CoA synthase and its derivatives.)
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Brownell JE, Sintchak MD, Gavin JM, et al. (2010) Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ. Molecular Cell. 37: 102-11
Tan X, Loke HK, Fitch S, et al. (2005) The tunnel of acetyl-coenzyme a synthase/carbon monoxide dehydrogenase regulates delivery of CO to the active site. Journal of the American Chemical Society. 127: 5833-9
Loke HK, Lindahl PA. (2003) Identification and preliminary characterization of AcsF, a putative Ni-insertase used in the biosynthesis of acetyl-CoA synthase from Clostridium thermoaceticum. Journal of Inorganic Biochemistry. 93: 33-40
Loke HK, Tan X, Lindahl PA. (2002) Genetic construction of truncated and chimeric metalloproteins derived from the alpha subunit of acetyl-CoA synthase from Clostridium thermoaceticum. Journal of the American Chemical Society. 124: 8667-72
Loke HK, Bennett GN, Lindahl PA. (2000) Active acetyl-CoA synthase from Clostridium thermoaceticum obtained by cloning and heterologous expression of acsAB in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 97: 12530-5
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