Jason C. O'Connor, Ph.D.

Affiliations: 
2005 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Immunology, Neuroscience Biology, Molecular Biology
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Gregory G. Freund grad student 2005 UIUC
 (Type 2 diabetes impairs interleukin-4 function in macrophages and amplifies the brain-based neuroimmune response.)
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Publications

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Rodriguez-Zas SL, Wu C, Southey BR, et al. (2018) Disruption of microglia histone acetylation and protein pathways in mice exhibiting inflammation-associated depression-like symptoms. Psychoneuroendocrinology. 97: 47-58
Laumet G, Zhou W, Dantzer R, et al. (2017) Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain. Brain, Behavior, and Immunity
Parrott JM, Redus L, O'Connor JC. (2016) Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge. Journal of Neuroinflammation. 13: 124
Gonzalez-Pena D, Nixon SE, O'Connor JC, et al. (2016) Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge. Plos One. 11: e0150858
Parrott JM, O'Connor JC. (2015) Kynurenine 3-Monooxygenase: An Influential Mediator of Neuropathology. Frontiers in Psychiatry. 6: 116
Dugan AM, Parrott JM, Redus L, et al. (2015) Low-level stress induces production of neuroprotective factors in wild-type but not BDNF+/- mice: interleukin-10 and kynurenic acid. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp)
Heisler JM, O'Connor JC. (2015) Indoleamine 2,3-dioxygenase-dependent neurotoxic kynurenine metabolism mediates inflammation-induced deficit in recognition memory. Brain, Behavior, and Immunity
Heisler JM, Morales J, Donegan JJ, et al. (2015) The attentional set shifting task: a measure of cognitive flexibility in mice. Journal of Visualized Experiments : Jove
Nixon SE, González-Peña D, Lawson MA, et al. (2015) Analytical workflow profiling gene expression in murine macrophages. Journal of Bioinformatics and Computational Biology. 13: 1550010
Rodriguez-Zas SL, Nixon SE, Lawson MA, et al. (2015) Advancing the understanding of behaviors associated with Bacille Calmette Guérin infection using multivariate analysis. Brain, Behavior, and Immunity. 44: 176-86
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