Parents

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Martin Karplus grad student 1993 MIT
Gregory A. Petsko grad student 1993 MIT
 (Studies of protein secondary structure (tight β-turns) and multiple binding sites to elastase)

Children

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Gregory K. Buhrman grad student 2005 NCSU
Nathan I. Nicely grad student 2005 NCSU
Michelle C. Dechene grad student 2008 NCSU
Genevieve A. Holzapfel grad student 2011 NCSU
Susan K. Fetics grad student 2012 NCSU
Bradley M. Kearney grad student 2012 NCSU
Alicia Y Volmar grad student 2014-2020 Northeastern University
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Publications

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Packer MR, Parker JA, Chung JK, et al. (2021) Raf promotes dimerization of the Ras G-domain with increased allosteric connections. Proceedings of the National Academy of Sciences of the United States of America. 118
Agarwal S, Smith M, De La Rosa I, et al. (2020) Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor. Acta Crystallographica. Section D, Structural Biology. 76: 1001-1014
Jang H, Banerjee A, Marcus K, et al. (2019) The Structural Basis of the Farnesylated and Methylated KRas4B Interaction with Calmodulin. Structure (London, England : 1993)
Johnson CW, Lin YJ, Reid D, et al. (2019) Isoform-Specific Destabilization of the Active Site Reveals a Molecular Mechanism of Intrinsic Activation of KRas G13D. Cell Reports. 28: 1538-1550.e7
Kearney BM, Schwabe M, Marcus K, et al. (2019) DRoP: Automated detection of conserved solvent binding sites on proteins. Proteins
Zhou H, Guterres H, Mattos C, et al. (2018) Predicting X-ray solution scattering from flexible macromolecules. Protein Science : a Publication of the Protein Society
Johnson CW, Reid D, Parker JA, et al. (2017) The small GTPases K-Ras, N-Ras and H-Ras have distinct biochemical properties determined by allosteric effects. The Journal of Biological Chemistry
Johnson CW, Buhrman G, Ting PY, et al. (2016) Expression, purification, crystallization and X-ray data collection for RAS and its mutants. Data in Brief. 6: 423-7
Knihtila R, Holzapfel G, Weiss K, et al. (2015) Neutron Crystal Structure of RAS GTPase puts in question the Protonation State of the GTP γ-Phosphate. The Journal of Biological Chemistry
Mattos C. (2015) Ras: structural details to guide direct targeting. Aging. 7: 344-5
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