Keith Brew

Affiliations: 
1974-2001 Biochemistry and Molecular Biology University of Miami, Coral Gables, FL 
 2001- Biomedical Science Florida Atlantic University, Boca Raton, FL, United States 
Area:
Biochemistry
Website:
http://med.fau.edu/home/departments/biomedical/brew.php
Google:
"Keith Brew"
Bio:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270236/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1270237/
http://www.jbc.org/content/242/16/3747.short

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Publications

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Manka SW, Brew K. (2020) Thermodynamic and mechanistic insights into coupled binding and unwinding of collagen by matrix metalloproteinase 1. Journal of Molecular Biology
Logue T, Lizotte-Waniewski M, Brew K. (2019) Thermodynamic profiles of the interactions of suramin, chondroitin sulfate, and pentosan polysulfate with the inhibitory domain of TIMP-3. Febs Letters
Zou H, Wu Y, Brew K. (2016) Thermodynamic basis of selectivity in the interactions of tissue inhibitors of metalloproteinases N-domains with matrix metalloproteinases -1, -3 and -14. The Journal of Biological Chemistry
Lizotte-Waniewski M, Brew K, Hennekens CH. (2015) Hypothesis: Metalloproteinase Inhibitors Decrease Risks of Cardiovascular Disease. Journal of Cardiovascular Pharmacology and Therapeutics
Pham TT, Stinson B, Thiyagarajan N, et al. (2014) Structures of complexes of a metal-independent glycosyltransferase GT6 from Bacteroides ovatus with UDP-N-acetylgalactosamine (UDP-GalNAc) and its hydrolysis products. The Journal of Biological Chemistry. 289: 8041-50
Brew K, Page-McCaw A. (2013) Dm1 and Dm2 Matrix Metallopeptidases Handbook of Proteolytic Enzymes. 1: 850-854
Brew K. (2013) α-Lactalbumin Advanced Dairy Chemistry: Volume 1a: Proteins: Basic Aspects, 4th Edition. 121-273
Thiyagarajan N, Pham TT, Stinson B, et al. (2012) Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Scientific Reports. 2: 940
Ashutosh, Chao C, Borgmann K, et al. (2012) Tissue inhibitor of metalloproteinases-1 protects human neurons from staurosporine and HIV-1-induced apoptosis: mechanisms and relevance to HIV-1-associated dementia. Cell Death & Disease. 3: e332
Bahudhanapati H, Zhang Y, Sidhu SS, et al. (2011) Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1)). The Journal of Biological Chemistry. 286: 31761-70
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