Robert H. Mach, Ph.D.
Affiliations: | 2013 | Chemistry | Washington University, Saint Louis, St. Louis, MO |
| 2013- | Radiology | University of Pennsylvania School of Medicine, Philadelphia, PA, United States |
Area:
General Chemistry, Pharmacy, Nuclear ChemistryWebsite:
https://www.med.upenn.edu/apps/faculty/index.php/g275/p8658246Google:
"Robert H Mach"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Wayne K. Anderson | grad student | 1985 | SUNY Buffalo | |
| (Potential prodrugs and radiation sensitizing analogs of the acylated vinylogous carbinolamine tumor inhibitors) | ||||
Children
Sign in to add trainee| Xin Peng | grad student | 2013 | Washington University |
| Zsófia Lengyel | post-doc | 2018- | University of Pennsylvania School of Medicine |
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Publications
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| Weng CC, Riad A, Lieberman BP, et al. (2022) Characterization of Sigma-2 Receptor-Specific Binding Sites Using [H]DTG and [I]RHM-4. Pharmaceuticals (Basel, Switzerland). 15 |
| Ferrie JJ, Lengyel-Zhand Z, Janssen B, et al. (2020) Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput screening. Chemical Science. 11: 12746-12754 |
| Ågren R, Zeberg H, Maciej Stępniewski T, et al. (2020) A ligand with two modes of interaction with the dopamine D2 receptor - An induced-fit mechanism of insurmountable antagonism. Acs Chemical Neuroscience |
| Zeng C, Riad A, Mach RH. (2020) The Biological Function of Sigma-2 Receptor/TMEM97 and Its Utility in PET Imaging Studies in Cancer. Cancers. 12 |
| Riad A, Lengyel-Zhand Z, Zeng C, et al. (2020) The Sigma-2 Receptor/TMEM97, PGRMC1, and LDL Receptor Complex Are Responsible for the Cellular Uptake of Aβ42 and Its Protein Aggregates. Molecular Neurobiology |
| McDonald ES, Doot RK, Young AJ, et al. (2019) Breast Cancer F-ISO-1 Uptake as a Marker of Proliferation Status. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine |
| Lee H, Riad A, Martorano P, et al. (2019) PARP-1-targeted Auger emitters display high-LET cytotoxic properties in vitro but show limited therapeutic utility in solid tumor models of human neuroblastoma. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine |
| Sellmyer MA, Richman SA, Lohith K, et al. (2019) Imaging CAR T Cell Trafficking with eDFHR as a PET Reporter Gene. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Janssen B, Mach RH. (2019) Development of brain PET imaging agents: Strategies for imaging neuroinflammation in Alzheimer's disease. Progress in Molecular Biology and Translational Science. 165: 371-399 |
| Chen PJ, Taylor M, Griffin SA, et al. (2019) Design, synthesis, and evaluation of N-(4-(4-phenyl piperazin-1-yl)butyl)-4-(thiophen-3-yl)benzamides as selective dopamine D receptor ligands. Bioorganic & Medicinal Chemistry Letters |