Paul Erhardt

Medicinal Chemistry The University of Toledo 
Pharmacy, Organic Chemistry, Oncology
"Paul Erhardt"
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Kress BJ, Kim DH, Mayo JR, et al. (2021) Synthesis and Evaluation of PPARδ Agonists That Promote Osteogenesis in a Human Mesenchymal Stem Cell Culture and in a Mouse Model of Human Osteoporosis. Journal of Medicinal Chemistry
Oppong F, Li Z, Fakhrabadi EA, et al. (2020) Investigating the potential to deliver and maintain plasma and brain levels of a novel practically insoluble methuosis inducing anticancer agent 5-methoxy MOMIPP through an injectable in situ forming thermoresponsive hydrogel formulation. Journal of Pharmaceutical Sciences
Gordon DM, Neifer KL, Hamoud AA, et al. (2020) Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α. The Journal of Biological Chemistry
Li Z, Mbah NE, Overmeyer JH, et al. (2019) The JNK signaling pathway plays a key role in methuosis (non-apoptotic cell death) induced by MOMIPP in glioblastoma. Bmc Cancer. 19: 77
Du S, Sarver JG, Trabbic CJ, et al. (2018) 6-MOMIPP, a novel brain-penetrant anti-mitotic indolyl-chalcone, inhibits glioblastoma growth and viability. Cancer Chemotherapy and Pharmacology
Trabbic CJ, George SM, Alexander EM, et al. (2016) Synthesis and biological evaluation of isomeric methoxy substitutions on anti-cancer indolyl-pyridinyl-propenones: Effects on potency and mode of activity. European Journal of Medicinal Chemistry. 122: 79-91
Kinzler AJ, Prokopiak ZA, Vaughan MM, et al. (2016) Cytochrome P450, CYP93A1, as a defense marker in soybean Biologia Plantarum. 1-7
Malik N, Zhang Z, Erhardt P. (2015) Total Synthesis of (±)-Glyceollin II and a Dihydro Derivative. Journal of Natural Products
Trabbic CJ, Overmeyer JH, Alexander EM, et al. (2015) Synthesis and biological evaluation of indolyl-pyridinyl-propenones having either methuosis or microtubule disruption activity. Journal of Medicinal Chemistry. 58: 2489-512
Trabbic CJ, Dietsch HM, Alexander EM, et al. (2014) Differential Induction of Cytoplasmic Vacuolization and Methuosis by Novel 2-Indolyl-Substituted Pyridinylpropenones. Acs Medicinal Chemistry Letters. 5: 73-77
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