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Percy Tumbale, Ph.D.

Affiliations: 
2009 Florida Atlantic University, Boca Raton, FL, United States 
Area:
Biochemistry, Biomedical Engineering, Molecular Biology
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"Percy Tumbale"
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Keith Brew grad student 2009 Florida Atlantic University
 (Structure-function relationships in eukaryotic and prokaryotic family 6 glycosyltransferases.)

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Thiyagarajan N, Pham TT, Stinson B, et al. (2012) Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Scientific Reports. 2: 940
Brew K, Tumbale P, Acharya KR. (2010) Family 6 glycosyltransferases in vertebrates and bacteria: inactivation and horizontal gene transfer may enhance mutualism between vertebrates and bacteria. The Journal of Biological Chemistry. 285: 37121-7
Tumbale P, Brew K. (2009) Characterization of a metal-independent CAZy family 6 glycosyltransferase from Bacteroides ovatus. The Journal of Biological Chemistry. 284: 25126-34
Jamaluddin H, Tumbale P, Ferns TA, et al. (2009) Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal). Biochemical and Biophysical Research Communications. 385: 601-4
Tumbale P, Jamaluddin H, Thiyagarajan N, et al. (2008) Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase. Glycobiology. 18: 1036-43
Tumbale P, Jamaluddin H, Thiyagarajan N, et al. (2008) Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity. Biochemistry. 47: 8711-8
Jamaluddin H, Tumbale P, Withers SG, et al. (2008) Corrigendum to "Conformational Changes Induced by Binding of UDP-2F-galactose to α-1,3 Galactosyltransferase-Implications for Catalysis" [J. Mol. Biol. 369 (2007) 1270-1281] (DOI:10.1016/j.jmb.2007.04.012) Journal of Molecular Biology. 378: 295-296
Jamaluddin H, Tumbale P, Withers SG, et al. (2007) Conformational Changes Induced by Binding UDP-2F-galactose to α-1,3 Galactosyltransferase- Implications for Catalysis Journal of Molecular Biology. 369: 1270-1281
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