James B. Wechuck, Ph.D.

Affiliations: 
2002 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Chemical Engineering, Biomedical Engineering, Cell Biology
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Mohammad M. Ataai grad student 2002 University of Pittsburgh
 (Production and purification of HSV-1 vectors and its use for gene transfer to human CD34+ cells.)
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Publications

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Goss JR, Krisky D, Bouch K, et al. (2016) 184. PGN-503, a Herpes Simplex Virus Based Vector Expressing Neurotrophin-3, Prevents and Reverses Neuropathy in a Mouse Model of Paclitaxel-Induced Peripheral Neuropathy Molecular Therapy. 24
Goss JR, Krisky D, Wechuck J, et al. (2014) Herpes simplex virus-based nerve targeting gene therapy in pain management. Journal of Pain Research. 7: 71-9
Okada H, Wolfe D, Wechuck J, et al. (2014) PD9-07 HERPES SIMPLEX VIRUS TYPE-1 (HSV-1) VECTOR-MEDIATED GENE THERAPY OF ENDOMORPHIN FOR BLADDER OVERACTIVITY AND NOCICEPTION Journal of Urology. 191
Goins WF, Krisky DM, Wechuck JB, et al. (2011) Generation of replication-competent and -defective HSV vectors. Cold Spring Harbor Protocols. 2011: pdb.prot5615
Wolfe D, Wechuck J, Krisky D, et al. (2009) A clinical trial of gene therapy for chronic pain. Pain Medicine (Malden, Mass.). 10: 1325-30
Kato R, Wolfe D, Coyle CH, et al. (2009) Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury. Gene Therapy. 16: 26-33
KATO R, BENNETT NE, KIM JH, et al. (2009) Gene Therapy for Neurogenic Erectile Dysfunction Luts: Lower Urinary Tract Symptoms. 1: S44-S47
Craft AM, Krisky DM, Wechuck JB, et al. (2008) Herpes simplex virus-mediated expression of Pax3 and MyoD in embryoid bodies results in lineage-Related alterations in gene expression profiles. Stem Cells (Dayton, Ohio). 26: 3119-29
Goins WF, Krisky DM, Wechuck JB, et al. (2008) Construction and production of recombinant herpes simplex virus vectors. Methods in Molecular Biology (Clifton, N.J.). 433: 97-113
Kato R, Wolfe D, Coyle CH, et al. (2007) Herpes simplex virus vector-mediated delivery of glial cell line-derived neurotrophic factor rescues erectile dysfunction following cavernous nerve injury. Gene Therapy. 14: 1344-52
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