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Swaminathan Murugappan, Ph.D.

Affiliations: 
2006 Temple University, Philadelphia, PA, United States 
Area:
Physiology Biology
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"Swaminathan Murugappan"
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Satya P. Kunapuli grad student 2006 Temple University
 (Regulation and function of protein kinase C isoforms in platelet activation.)

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Publications

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Chari R, Kim S, Murugappan S, et al. (2009) Lyn, PKC-delta, SHIP-1 interactions regulate GPVI-mediated platelet-dense granule secretion. Blood. 114: 3056-63
Chari R, Getz T, Nagy B, et al. (2009) Protein kinase C[delta] differentially regulates platelet functional responses. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 699-705
Murugappan S, Chari R, Palli VM, et al. (2009) Differential regulation of threonine and tyrosine phosphorylations on protein kinase Cdelta by G-protein-mediated pathways in platelets. The Biochemical Journal. 417: 113-20
Garcia A, Shankar H, Murugappan S, et al. (2007) Regulation and functional consequences of ADP receptor-mediated ERK2 activation in platelets. The Biochemical Journal. 404: 299-308
Kahner BN, Shankar H, Murugappan S, et al. (2006) Nucleotide receptor signaling in platelets. Journal of Thrombosis and Haemostasis : Jth. 4: 2317-26
Murugappa S, Kunapuli SP. (2006) The role of ADP receptors in platelet function. Frontiers in Bioscience : a Journal and Virtual Library. 11: 1977-86
Murugappan S, Shankar H, Bhamidipati S, et al. (2005) Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Blood. 106: 550-7
Dorsam RT, Kim S, Murugappan S, et al. (2005) Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways. Blood. 105: 2749-56
Murugappan S, Shankar H, Kunapuli SP. (2004) Platelet receptors for adenine nucleotides and thromboxane A2. Seminars in Thrombosis and Hemostasis. 30: 411-8
Shankar H, Murugappan S, Kim S, et al. (2004) Role of G protein-gated inwardly rectifying potassium channels in P2Y12 receptor-mediated platelet functional responses. Blood. 104: 1335-43
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