Melissa K. Passarelli, Ph.D.

Affiliations: 
2011 Pennsylvania State University, State College, PA, United States 
Area:
Analytical Chemistry, Biochemistry
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Nicholas Winograd grad student 2011 Penn State
 (Lipid characterization with time-of-flight secondary ion mass spectrometry (TOF-SIMS).)
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Publications

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Race AM, Rae A, Vorng JL, et al. (2020) Correlative hyper-spectral imaging using a dimensionality reduction based image fusion method. Analytical Chemistry
Aoyagi S, Kodama Y, Passarelli MK, et al. (2019) OrbiSIMS imaging identifies molecular constituents of the perialgal vacuole membrane of with symbiotic . Analytical Chemistry
Passarelli MK, Pirkl A, Moellers R, et al. (2017) The 3D OrbiSIMS-label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power. Nature Methods
Newman CF, Havelund R, Passarelli MK, et al. (2017) Intracellular drug uptake - a comparison of single cell measurements using ToF-SIMS imaging and quantification from cell populations with LC-MS/MS. Analytical Chemistry
Jiang H, Passarelli MK, Munro PM, et al. (2017) High-resolution sub-cellular imaging by correlative NanoSIMS and electron microscopy of amiodarone internalisation by lung macrophages as evidence for drug-induced phospholipidosis. Chemical Communications (Cambridge, England)
Vorng JL, Kotowska AM, Passarelli MK, et al. (2016) Semi-empirical rules to determine drug sensitivity and ionization efficiency in SIMS using a model tissue sample. Analytical Chemistry
Yokoyama Y, Aoyagi S, Fujii M, et al. (2016) Peptide Fragmentation and Surface Structural Analysis by Means of ToF-SIMS Using Large Cluster Ion Sources. Analytical Chemistry. 88: 3592-7
Passarelli MK, Newman CF, Marshall PS, et al. (2015) Single-Cell Analysis: Visualizing Pharmaceutical and Metabolite Uptake in Cells with Label-Free 3D Mass Spectrometry Imaging. Analytical Chemistry
Passarelli MK, Wang J, Mohammadi AS, et al. (2014) Development of an organic lateral resolution test device for imaging mass spectrometry. Analytical Chemistry. 86: 9473-80
Passarelli MK, Ewing AG. (2013) Single-cell imaging mass spectrometry. Current Opinion in Chemical Biology. 17: 854-9
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