Jacob D. Estes, Ph.D.

Affiliations: 
2003 Brigham Young University, Provo, UT, United States 
Area:
Microbiology Biology, Molecular Biology, Pathology, Immunology
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Gregory F. Burton grad student 2003 BYU
 (Follicular dendritic cell contributions to the germinal center microenvironment and their role in human immunodeficiency virus pathogenesis.)
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Publications

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Okoye AA, Duell DD, Fukazawa Y, et al. (2021) CD8+ T cells fail to limit SIV reactivation following ART withdrawal until after viral amplification. The Journal of Clinical Investigation
Swanstrom AE, Immonen TT, Oswald K, et al. (2021) Antibody-mediated depletion of viral reservoirs is limited in SIV-infected macaques treated early with antiretroviral therapy. The Journal of Clinical Investigation
Raehtz KD, Barrenäs F, Xu C, et al. (2020) African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333
Deleage C, Immonen TT, Fennessey CM, et al. (2019) Defining early SIV replication and dissemination dynamics following vaginal transmission. Science Advances. 5: eaav7116
Hensley-McBain T, Berard AR, Manuzak JA, et al. (2018) Intestinal damage precedes mucosal immune dysfunction in SIV infection. Mucosal Immunology
Del Prete GQ, Keele BF, Fode J, et al. (2017) A single gp120 residue can affect HIV-1 tropism in macaques. Plos Pathogens. 13: e1006572
Hansen SG, Piatak M, Ventura AB, et al. (2017) Addendum: Immune clearance of highly pathogenic SIV infection. Nature
Fennessey CM, Pinkevych M, Immonen TT, et al. (2017) Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy. Plos Pathogens. 13: e1006359
Osuna CE, Lim SY, Deleage C, et al. (2016) Zika viral dynamics and shedding in rhesus and cynomolgus macaques. Nature Medicine
Deleage C, Turkbey B, Estes JD. (2016) Imaging lymphoid tissues in nonhuman primates to understand SIV pathogenesis and persistence. Current Opinion in Virology. 19: 77-84
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