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Brian A. Carr, Ph.D.

Affiliations: 
2003 University of Utah, Salt Lake City, UT 
Area:
Pharmacology, Toxicology
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Garold S. Yost grad student 2003 University of Utah
 (Function and regulation of pulmonary expressed cytochrome P450 enzymes.)

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Hariparsad N, Carr BA, Evers R, et al. (2008) Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 1046-55
Tang C, Carr BA, Poignant F, et al. (2008) CYP2C75-involved autoinduction of metabolism in rhesus monkeys of methyl 3-chloro-3'-fluoro-4'-{(1R)-1-[({1-[(trifluoroacetyl)amino]cyclopropyl}carbonyl)amino]ethyl}-1,1'-biphenyl-2-carboxylate (MK-0686), a bradykinin B1 receptor antagonist. The Journal of Pharmacology and Experimental Therapeutics. 325: 935-46
Ma B, Carr BA, Krolikowski P, et al. (2007) Cytotoxicity of a Quinone-containing Cockroach Sex Pheromone in Human Lung Adenocarcinoma Cells. Chemical Research in Toxicology. 20: 72-8
Prueksaritanont T, Li C, Tang C, et al. (2006) Rifampin induces the in vitro oxidative metabolism, but not the in vivo clearance of diclofenac in rhesus monkeys. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1806-10
Prueksaritanont T, Kuo Y, Tang C, et al. (2006) In vitro and in vivo CYP3A64 induction and inhibition studies in rhesus monkeys: a preclinical approach for CYP3A-mediated drug interaction studies. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 34: 1546-55
Wan J, Carr BA, Cutler NS, et al. (2005) Sp1 and Sp3 regulate basal transcription of the human CYP2F1 gene. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 33: 1244-53
Cui D, Booth-Genthe CL, Carlini E, et al. (2004) Heterotropic modulation of sulfotransferase 2A1 activity by celecoxib: product ratio switching of ethynylestradiol sulfation. Drug Metabolism and Disposition. 32: 1260-1264
Reilly CA, Taylor JL, Lanza DL, et al. (2003) Capsaicinoids cause inflammation and epithelial cell death through activation of vanilloid receptors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 170-81
Carr BA, Ramakanth S, Dannan GA, et al. (2003) Characterization of pulmonary CYP4B2, specific catalyst of methyl oxidation of 3-methylindole. Molecular Pharmacology. 63: 1137-47
Carr BA, Wan J, Hines RN, et al. (2003) Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif. The Journal of Biological Chemistry. 278: 15473-83
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