Jessica M. Weems, Ph.D.

Affiliations: 
2010 Pharmacology and Toxicology University of Utah, Salt Lake City, UT 
Area:
Toxicology, Pharmacology
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Garold S. Yost grad student 2010 University of Utah
 (Potent 3-methylindole-mediated DNA damage, cytochrome p450 induction, and mutagenicity in human lung.)
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Weems JM, Lamb JG, D'Agostino J, et al. (2010) Potent mutagenicity of 3-methylindole requires pulmonary cytochrome P450-mediated bioactivation: a comparison to the prototype cigarette smoke mutagens B(a)P and NNK. Chemical Research in Toxicology. 23: 1682-90
Weems JM, Yost GS. (2010) 3-Methylindole metabolites induce lung CYP1A1 and CYP2F1 enzymes by AhR and non-AhR mechanisms, respectively. Chemical Research in Toxicology. 23: 696-704
Weems JM, Cutler NS, Moore C, et al. (2009) 3-Methylindole is mutagenic and a possible pulmonary carcinogen. Toxicological Sciences : An Official Journal of the Society of Toxicology. 112: 59-67
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