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Shama Moktan, Ph.D.

Affiliations: 
2011 The University of Mississippi Medical Center, Jackson, MS, United States 
Area:
Biochemistry
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Drazen Raucher grad student 2011 University of Mississippi Medical Center
 (Thermally Targeted Delivery of Small Molecule Drugs and Proapoptotic Peptides Using Elastin-like Polypeptides: In Vitro and In Vivo Studies.)

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Publications

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Moktan S, Raucher D. (2012) Anticancer activity of proapoptotic peptides is highly improved by thermal targeting using elastin-like polypeptides. International Journal of Peptide Research and Therapeutics. 18: 227-237
Moktan S, Perkins E, Kratz F, et al. (2012) Thermal targeting of an acid-sensitive doxorubicin conjugate of elastin-like polypeptide enhances the therapeutic efficacy compared with the parent compound in vivo. Molecular Cancer Therapeutics. 11: 1547-56
Moktan S, Ryppa C, Kratz F, et al. (2012) A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis. Investigational New Drugs. 30: 236-48
Moktan S, Perkins E, Kratz F, et al. (2011) Abstract 4440: Anti-tumor activity of a thermally responsive polypeptide-doxorubicin conjugate in a syngeneic mouse breast cancer model Cancer Research. 71: 4440-4440
Raucher D, Moktan S. (2011) Thermo-Responsive Polymers Drug Delivery in Oncology: From Basic Research to Cancer Therapy. 2: 667-700
Massodi I, Moktan S, Rawat A, et al. (2010) Inhibition of ovarian cancer cell proliferation by a cell cycle inhibitory peptide fused to a thermally responsive polypeptide carrier. International Journal of Cancer. 126: 533-44
Moktan S, Raucher D. (2010) Abstract 5520: Thermally targeted proapoptotic peptide for cancer therapy Cancer Research. 70: 5520-5520
Raucher D, Moktan S, Massodi I, et al. (2009) Therapeutic peptides for cancer therapy. Part II - cell cycle inhibitory peptides and apoptosis-inducing peptides. Expert Opinion On Drug Delivery. 6: 1049-64
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