Lior Izhar, Ph.D.

Affiliations: 
2009 BIC Biochemistry Weizmann Institute of Science, Rehovot, Israel 
 2015- Emendo Biotherapeutics 
Area:
Biochemistry, Microbiology Biology, Cell Biology
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"Lior Izhar"
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Parents

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Zvi Livneh grad student 2009 Weizmann Institute
 (Analysis of DNA Damage Tolerance Mechanisms in E. coli and Human Cells Using Plasmid and Chromosomal Lesion-Specific Probes.)
Stephen J. Elledge post-doc 2010-2015 Harvard Medical School
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Publications

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Izhar L, Adamson B, Ciccia A, et al. (2015) A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors. Cell Reports. 11: 1486-500
Ciccia A, Huang JW, Izhar L, et al. (2014) Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response. Proceedings of the National Academy of Sciences of the United States of America. 111: 18631-6
Izhar L, Ziv O, Cohen IS, et al. (2013) Genomic assay reveals tolerance of DNA damage by both translesion DNA synthesis and homology-dependent repair in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E1462-9
Ciccia A, Nimonkar AV, Hu Y, et al. (2012) Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress. Molecular Cell. 47: 396-409
Emanuele MJ, Elia AEH, Xu Q, et al. (2012) Erratum: Global identification of modular cullin-ring ligase substrates (Cell (2011) 147 (459-475)) Cell. 148: 620-622
Emanuele MJ, Elia AEH, Xu Q, et al. (2011) Global identification of modular cullin-RING ligase substrates Cell. 147: 459-474
Adar S, Izhar L, Hendel A, et al. (2009) Repair of gaps opposite lesions by homologous recombination in mammalian cells. Nucleic Acids Research. 37: 5737-48
Izhar L, Goldsmith M, Dahan R, et al. (2008) Analysis of strand transfer and template switching mechanisms of DNA gap repair by homologous recombination in Escherichia coli: predominance of strand transfer. Journal of Molecular Biology. 381: 803-9
Berdichevsky A, Izhar L, Livneh Z. (2002) Error-free recombinational repair predominates over mutagenic translesion replication in E. coli. Molecular Cell. 10: 917-24
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