Julie S. Barber-Rotenberg, Ph.D.
Affiliations: | 2012 | Tumor Biology | Georgetown University, Washington, DC |
Area:
Oncology, BiochemistryGoogle:
"Julie Barber-Rotenberg"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Jeffrey A. Toretsky | grad student | 2012 | Georgetown | |
| (EWS-FLI1 as a molecular target: Small molecule inhibitors for a disordered protein.) | ||||
| Ronen Marmorstein | post-doc | Penn | ||
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Publications
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| Rebecca VW, Nicastri MC, Fennelly C, et al. (2018) PPT1 promotes tumor growth and is the molecular target of chloroquine derivatives in cancer. Cancer Discovery |
| Rebecca VW, Nicastri MC, McLaughlin N, et al. (2017) A unified approach to targeting the lysosome's degradative and growth signaling roles. Cancer Discovery |
| Qin J, Rajaratnam R, Feng L, et al. (2015) Development of organometallic S6K1 inhibitors. Journal of Medicinal Chemistry. 58: 305-14 |
| Hong SH, Youbi SE, Hong SP, et al. (2014) Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in Ewing Sarcoma. Oncotarget. 5: 338-50 |
| Schlottmann S, Erkizan HV, Barber-Rotenberg JS, et al. (2012) Acetylation Increases EWS-FLI1 DNA Binding and Transcriptional Activity. Frontiers in Oncology. 2: 107 |
| Barber-Rotenberg JS, Selvanathan SP, Kong Y, et al. (2012) Single enantiomer of YK-4-279 demonstrates specificity in targeting the oncogene EWS-FLI1. Oncotarget. 3: 172-82 |
| Erkizan HV, Scher LJ, Gamble SE, et al. (2011) Novel peptide binds EWS-FLI1 and reduces the oncogenic potential in Ewing tumors. Cell Cycle (Georgetown, Tex.). 10: 3397-408 |
| Erkizan HV, Scher LM, Gamble E, et al. (2011) Abstract 259: Novel peptide directed targeting of EWS-FLI1 impairs tumor cell growth Cancer Research. 71: 259-259 |
| Schlottmann S, Erkizan HV, Barber-Rotenberg J, et al. (2010) Abstract 3897: EWS-FLI1 is regulated by acetylation Cancer Research. 70: 3897-3897 |
| Toretsky JA, Erkizan HV, Kong Y, et al. (2010) Abstract 3411: Targeting of EWS-FLI1 with small molecule YK-4-279 reduces xenograft growth by disruption of disordered protein-protein interactions Cancer Research. 70: 3411-3411 |