Sushabhan Sadhukhan, Ph.D.

Affiliations: 
2012 Chemistry Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Biochemistry
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Gregory P. Tochtrop grad student 2012 Case Western
 (Metabolism & signaling of 4-hydroxyacids: Novel metabolic pathways and insight into the signaling of lipid peroxidation products.)
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Publications

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Tong Z, Wang M, Wang Y, et al. (2016) SIRT7 Is an RNA-Activated Protein Lysine Deacylase. Acs Chemical Biology
Sadhukhan S, Liu X, Ryu D, et al. (2016) Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. Proceedings of the National Academy of Sciences of the United States of America
Liu X, Sadhukhan S, Sun S, et al. (2015) High-Resolution Metabolomics with Acyl-CoA Profiling Reveals Widespread Remodeling in Response to Diet. Molecular & Cellular Proteomics : McP. 14: 1489-500
Jin Z, Berthiaume JM, Li Q, et al. (2014) Catabolism of (2E)-4-hydroxy-2-nonenal via ω- and ω-1-oxidation stimulated by ketogenic diet. The Journal of Biological Chemistry. 289: 32327-38
Gatbonton-Schwager TN, Sadhukhan S, Zhang GF, et al. (2014) Identification of a negative feedback loop in biological oxidant formation fegulated by 4-hydroxy-2-(E)-nonenal. Redox Biology. 2: 755-63
Sadhukhan S, Zhang GF, Tochtrop GP. (2014) Modular isotopomer synthesis of γ-hydroxybutyric acid for a quantitative analysis of metabolic fates. Acs Chemical Biology. 9: 1706-11
Sadhukhan S, Han Y, Jin Z, et al. (2014) Glutathionylated 4-hydroxy-2-(E)-alkenal enantiomers in rat organs and their contributions toward the disposal of 4-hydroxy-2-(E)-nonenal in rat liver. Free Radical Biology & Medicine. 70: 78-85
Yu J, Sadhukhan S, Noriega LG, et al. (2013) Metabolic characterization of a Sirt5 deficient mouse model. Scientific Reports. 3: 2806
Li Q, Sadhukhan S, Berthiaume JM, et al. (2013) 4-Hydroxy-2(E)-nonenal (HNE) catabolism and formation of HNE adducts are modulated by β oxidation of fatty acids in the isolated rat heart. Free Radical Biology & Medicine. 58: 35-44
Harris SR, Zhang GF, Sadhukhan S, et al. (2013) Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate. Chemical Research in Toxicology. 26: 213-20
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