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Jiangbo Tang, Ph.D.

Affiliations: 
2010 University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Molecular Biology, Oncology, Genetics
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"Jiangbo Tang"
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Robert W. Sobol grad student 2010 University of Pittsburgh
 (Glioma chemotherapy sensitization mediated by base excision repair inhibition and its potential application.)

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Tang J, Cho NW, Cui G, et al. (2013) Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nature Structural & Molecular Biology. 20: 317-25
Svilar D, Dyavaiah M, Brown AR, et al. (2012) Alkylation sensitivity screens reveal a conserved cross-species functionome. Molecular Cancer Research : McR. 10: 1580-96
Goellner EM, Grimme B, Brown AR, et al. (2011) Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Research. 71: 2308-17
Tang JB, Svilar D, Trivedi RN, et al. (2011) N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Neuro-Oncology. 13: 471-86
Tang JB, Greenberg RA. (2010) Connecting the Dots: Interplay between Ubiquitylation and SUMOylation at DNA Double-Strand Breaks. Genes & Cancer. 1: 787-96
Jelezcova E, Trivedi RN, Wang XH, et al. (2010) Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Mutation Research. 686: 57-67
Tang JB, Goellner EM, Wang XH, et al. (2010) Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Molecular Cancer Research : McR. 8: 67-79
Trivedi RN, Wang XH, Jelezcova E, et al. (2008) Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide. Molecular Pharmacology. 74: 505-16
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