Yaakov Kacher, Ph.D.

Affiliations: 
2009 BCH Biological Chemistry Weizmann Institute of Science, Rehovot, Israel 
Area:
Biochemistry, Cell Biology, Pathology
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"Yaakov Kacher"
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Parents

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Anthony H. Futerman grad student 2009 Weizmann Institute
 (Cell biology of Gaucher disease:pathological mechanisms and therapy.)
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Publications

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Kacher Y, Futerman AH. (2009) Impaired IL-10 transcription and release in animal models of Gaucher disease macrophages. Blood Cells, Molecules & Diseases. 43: 134-7
Kacher Y, Brumshtein B, Boldin-Adamsky S, et al. (2008) Acid β-glucosidase: Insights from structural analysis and relevance to Gaucher disease therapy Biological Chemistry. 389: 1361-1369
Kacher Y, Golan A, Pewzner-Jung Y, et al. (2007) Changes in macrophage morphology in a Gaucher disease model are dependent on CTP:phosphocholine cytidylyltransferase alpha. Blood Cells, Molecules & Diseases. 39: 124-9
Kacher Y, Futerman AH. (2006) Genetic diseases of sphingolipid metabolism: pathological mechanisms and therapeutic options. Febs Letters. 580: 5510-7
Kacher Y, Futerman AH. (2006) Neuronal cell death in glycosphingolipidoses Sphingolipid Biology. 285-293
Raas-Rothschild A, Pankova-Kholmyansky I, Kacher Y, et al. (2004) Glycosphingolipidoses: beyond the enzymatic defect. Glycoconjugate Journal. 21: 295-304
Ginzburg L, Kacher Y, Futerman AH. (2004) The pathogenesis of glycosphingolipid storage disorders. Seminars in Cell & Developmental Biology. 15: 417-31
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