Daniel P. Flaherty, Ph.D.

Affiliations: 
2015- Purdue University, West Lafayette, IN, United States 
Area:
Pharmaceutical Chemistry, Biochemistry, Organic Chemistry
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Parents

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Jonathan L. Vennerstrom grad student 2010 University of Nebraska Medical Center
 (Bis-styrylbenzenes and their potential in Alzheimer's disease.)
Jeffrey Aube post-doc 2010-2014 University of Kansas
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Publications

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Holly KJ, Kataria A, Flaherty DP, et al. (2024) Unguarded liabilities: complex amino acid dependence exposes unique avenues of inhibition. Frontiers in Antibiotics. 3: 1395425
Camara A, Chugh H, George A, et al. (2024) Discovery and Validation of a Novel Inhibitor of HYPE-mediated AMPylation. Cell Stress & Chaperones
Imhoff RD, Rosenthal MR, Ashraf K, et al. (2023) Identification of covalent fragment inhibitors for Plasmodium falciparum UCHL3 with anti-malarial efficacy. Bioorganic & Medicinal Chemistry Letters. 94: 129458
Dwyer TS, O'Brien JB, Ptak CP, et al. (2022) Protein-protein interaction-based high throughput screening for adenylyl cyclase 1 inhibitors: Design, implementation, and discovery of a novel chemotype. Frontiers in Pharmacology. 13: 977742
Chojnacki M, Cao X, Flaherty DP, et al. (2021) Optimization of 2-Acylaminocycloalkylthiophene Derivatives for Activity against RnpA. Antibiotics (Basel, Switzerland). 10
Krabill AD, Chen H, Hussain S, et al. (2021) Optimization and Anti-Cancer Properties of Fluoromethylketones as Covalent Inhibitors for Ubiquitin C-Terminal Hydrolase L1. Molecules (Basel, Switzerland). 26
Colquhoun JM, Ha L, Beckley A, et al. (2019) Identification of Small Molecule Inhibitors of RnpA. Antibiotics (Basel, Switzerland). 8
Flaherty DP, Harris MT, Schroeder CE, et al. (2017) Optimization and Evaluation of Antiparasitic Benzamidobenzoic Acids as Inhibitors of Kinetoplastid Hexokinase 1. Chemmedchem
Hackler A, Patrick SL, Kahney EW, et al. (2017) Antiparasitic lethality of sulfonamidebenzamides in kinetoplastids. Bioorganic & Medicinal Chemistry Letters
Lopez-Sambrooks C, Shrimal S, Khodier C, et al. (2016) Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. Nature Chemical Biology
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