Jeffrey D. Klenc, Ph.D.

Affiliations: 
2010 Georgia State University, Atlanta, GA, United States 
Area:
Organic Chemistry
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"Jeffrey Klenc"
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Lucjan Strekowski grad student 2010 Georgia State
 (Design and synthesis of novel serotonin receptor ligands.)
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Publications

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Lipowska M, Klenc J, Taylor AT, et al. (2019) -Tc/Re-tricarbonyl complexes with tridentate aminocarboxyphosphonate ligands: suitability of the phosphonate group in chelate ligand design of new imaging agents. Inorganica Chimica Acta. 486: 529-537
Lipowska M, Klenc J, Jarkas N, et al. (2016) Monoanionic (99m)Tc-tricarbonyl-aminopolycarboxylate complexes with uncharged pendant groups: Radiosynthesis and evaluation as potential renal tubular tracers. Nuclear Medicine and Biology. 47: 48-55
Strekowski L, Sączewski J, Raux EA, et al. (2016) Synthesis and Structure-Activity Relationship Analysis of 5-HT₇ Receptor Antagonists: Piperazin-1-yl Substituted Unfused Heterobiaryls. Molecules (Basel, Switzerland). 21
Klenc J, Lipowska M, Abhayawardhana PL, et al. (2015) Structure and Properties of fac-[Re(I)(CO)3(NTA)](2-) (NTA(3-) = Trianion of Nitrilotriacetic Acid) and fac-[Re(I)(CO)3(L)](n-) Analogues Useful for Assessing the Excellent Renal Clearance of the fac-[(99m)Tc(I)(CO)3(NTA)](2-) Diagnostic Renal Agent. Inorganic Chemistry. 54: 6281-90
Klenc J, Lipowska M, Taylor AT. (2015) Identification of lead compounds for (99m)Tc and (18)F GPR91 radiotracers. Bioorganic & Medicinal Chemistry Letters. 25: 2335-9
Klenc J, Lipowska M, Taylor AT, et al. (2012) Synthesis and characterization of fac-Re(CO)3-aspartic-N-monoacetic acid, a structural analogue of a potential new renal tracer, fac-(99m)Tc(CO)3(ASMA). European Journal of Inorganic Chemistry. 2012
Lipowska M, Klenc J, Marzilli LG, et al. (2012) Preclinical evaluation of 99mTc(CO)3-aspartic-N-monoacetic acid, a renal radiotracer with pharmacokinetic properties comparable to 131I-o-iodohippurate. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 53: 1277-83
Cegla MT, Baran M, Czarny A, et al. (2011) The -NH-(C=)-Br functionality of heteroaromatic compounds as a synthon for fused dihydrooxazoles Journal of Heterocyclic Chemistry. 48: 720-723
Raux E, Klenc J, Blake A, et al. (2010) Conjugate addition of nucleophiles to the vinyl function of 2-chloro-4-vinylpyrimidine derivatives. Molecules (Basel, Switzerland). 15: 1973-84
Klenc J, Strekowski L. (2010) Synthesis of piperazino-substituted benzo[b]furans as potential CNS agents Heterocyclic Communications. 16: 249-252
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