William Guerrant, Ph.D.

2012 Georgia Institute of Technology, Atlanta, GA 
Biochemistry, Pharmaceutical Chemistry, Oncology
"William Guerrant"
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Adegboyega Oyelere grad student 2012 Georgia Tech
 (Targeted Histone Deacetylase Inhibition.)
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Guerrant W, Kota S, Troutman S, et al. (2016) YAP mediates tumorigenesis in neurofibromatosis type 2 by promoting cell survival and proliferation through a COX2-EGFR signaling axis. Cancer Research
Moleirinho S, Guerrant W, Kissil JL. (2014) The Angiomotins--from discovery to function. Febs Letters. 588: 2693-703
Guerrant W, Patil V, Canzoneri JC, et al. (2013) Dual-acting histone deacetylase-topoisomerase I inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 3283-7
Guerrant W, Patil V, Canzoneri JC, et al. (2012) Dual targeting of histone deacetylase and topoisomerase II with novel bifunctional inhibitors. Journal of Medicinal Chemistry. 55: 1465-77
Gryder BE, Guerrant W, Chen CH, et al. (2011) Oxathiazole-2-one derivative of bortezomib: Synthesis, stability and proteasome inhibition activity Medchemcomm. 2: 1083-1086
Mwakwari SC, Guerrant W, Patil V, et al. (2010) Non-peptide macrocyclic histone deacetylase inhibitors derived from tricyclic ketolide skeleton Journal of Medicinal Chemistry. 53: 6100-6111
Mwakwari SC, Patil V, Guerrant W, et al. (2010) Macrocyclic histone deacetylase inhibitors. Current Topics in Medicinal Chemistry. 10: 1423-40
Guerrant W, Mwakwari SC, Chen PC, et al. (2010) A structure-activity relationship study of the antimalarial and antileishmanial activities of nonpeptide macrocyclic histone deacetylase inhibitors. Chemmedchem. 5: 1232-5
Patil V, Guerrant W, Chen PC, et al. (2010) Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group. Bioorganic & Medicinal Chemistry. 18: 415-25
Oyelere AK, Chen PC, Guerrant W, et al. (2009) Non-peptide macrocyclic histone deacetylase inhibitors. Journal of Medicinal Chemistry. 52: 456-68
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