Scott A. Ezell, Ph.D.
Affiliations: | 2012 | Biochemistry | Sackler School of Graduate Biomedical Sciences (Tufts University) |
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Sign in to add mentor| Philip N. Tsichlis | grad student | 2012 | Sackler School of Graduate Biomedical Sciences (Tufts University) | |
| (The regulation of interferon signaling and ER stress response by different Akt isoforms.) | ||||
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Publications
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| Kuo HP, Ezell SA, Schweighofer KJ, et al. (2017) Combination of Ibrutinib and ABT-199 in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma. Molecular Cancer Therapeutics |
| Ezell SA, Wang S, Bihani T, et al. (2016) Differential regulation of mTOR signaling determines sensitivity to AKT inhibition in diffuse large B cell lymphoma. Oncotarget |
| Bihani T, Ezell SA, Ladd B, et al. (2015) Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers. Oncotarget. 6: 2407-20 |
| Ezell SA, Mayo M, Bihani T, et al. (2014) Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma. Oncotarget. 5: 4990-5001 |
| Kottakis F, Foltopoulou P, Sanidas I, et al. (2014) NDY1/KDM2B functions as a master regulator of polycomb complexes and controls self-renewal of breast cancer stem cells. Cancer Research. 74: 3935-46 |
| Sourvinos G, Morou A, Sanidas I, et al. (2014) The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection. Plos Pathogens. 10: e1004136 |
| Sanidas I, Polytarchou C, Hatziapostolou M, et al. (2014) Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. Molecular Cell. 53: 577-90 |
| Sourvinos G, Morou A, Sanidas I, et al. (2014) NDY1/KDM2B, EZH2 and JARID2 are selectively required for the infection of human foreskin fibroblasts with HCMV whereas the H3K27me3 demethylase JMJD3 inhibits viral infection. Plos Pathogens |
| Sanidas I, Polytarchou C, Hatziapostolou M, et al. (2014) Abstract 4777: A phosphoproteomics analysis reveals Akt isoform-specific signals that link RNA splicing to non-small cell lung cancer Cancer Research. 74: 4777-4777 |
| Kim HG, Tan L, Weisberg EL, et al. (2013) Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor. Acs Chemical Biology. 8: 2145-50 |