William H. Nugent, Ph.D.

Affiliations: 
2010 Physiology Virginia Commonwealth University, Richmond, VA, United States 
Area:
Physiology Biology
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Roland N. Pittman grad student 2010 VCU
 (In vivo measurement of rat skeletal muscle oxygen consumption following brief periods of ischemia with reperfusion as assessed by phosphorescence quenching microscopy.)
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Nugent WH, Sheppard FR, Vandegriff KD, et al. (2023) Exchange Transfusion with VS-101: A New PEGylated-Hb Designed to Restore Perfusion and Increase O2 Carrying Capacity. Shock (Augusta, Ga.)
Golub AS, Song BK, Nugent WH, et al. (2023) Dynamics of PO and VO in resting and contracting rat spinotrapezius muscle. Frontiers in Physiology. 14: 1172834
Nugent WH, Carr DA, Friedman J, et al. (2023) Novel transdermal curcumin therapeutic preserves endothelial barrier function in a high-dose LPS rat model. Artificial Cells, Nanomedicine, and Biotechnology. 51: 33-40
Carr DA, Nugent WH, Bruce ED, et al. (2022) Evaluation of an Injectable, Solid-State, Oxygen-Delivering Compound (Ox66) in a Rodent Model of Pulmonary Dysfunction-Induced Hypoxia. Military Medicine
Nugent WH, Carr DA, MacBryde R, et al. (2021) Gavage approach to oxygen supplementation with oxygen therapeutic Ox66™ in a hypoventilation rodent model of respiratory distress. Artificial Cells, Nanomedicine, and Biotechnology. 49: 709-716
Golub AS, Nugent WH, Song BK. (2021) Spike of interstitial PO produced by a twitch in rhythmically contracted muscle. Physiological Reports. 9: e14699
Song BK, Light WR, Vandegriff KD, et al. (2020) Systemic and microvascular comparison of Lactated Ringer's solution, VIR-HBOC, and alpha-alpha crosslinked haemoglobin-based oxygen carrier in a rat 10% topload model. Artificial Cells, Nanomedicine, and Biotechnology. 48: 1079-1088
Nugent WH, Carr DA, Macko AR, et al. (2020) Physiological and microvascular responses to hemoglobin concentration-targeted hemolytic anemia in rats. Journal of Applied Physiology (Bethesda, Md. : 1985). 128: 1579-1586
Macko A, Sheppard FR, Nugent WH, et al. (2020) Improved Hemodynamic Recovery and 72-Hour Survival Following Low-Volume Resuscitation with a PEGylated Carboxyhemoglobin in a Rat Model of Severe Hemorrhagic Shock. Military Medicine
Nugent WH, Sheppard FR, Dubick MA, et al. (2019) Microvascular and Systemic Impact of Resuscitation with Pegylated Carboxyhemoglobin-Based Oxygen Carrier or Hetastarch In A Rat Model of transient hemorrhagic Shock. Shock (Augusta, Ga.)
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