Kiem Vu, Ph.D.

Affiliations: 
2012 Pharmacology and Toxicology University of California, Davis, Davis, CA 
Area:
Cell Biology, Pharmacy, Biochemistry
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"Kiem Vu"
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Parents

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Angie Gelli grad student 2012 UC Davis
 (Metalloprotease and CCH1/MID1 calcium channel are promising drug targets to treat cryptococcosis.)
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Publications

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Vu K, Blumwald E, Gelli A. (2021) The Antifungal Activity of HMA, an Amiloride Analog and Inhibitor of Na/H Exchangers. Frontiers in Microbiology. 12: 673035
Aaron PA, Vu K, Gelli A. (2020) An Antivirulence Approach for Preventing Cryptococcus neoformans from Crossing the Blood-Brain Barrier via Novel Natural Product Inhibitors of a Fungal Metalloprotease. Mbio. 11
Vu K, Garcia JA, Gelli A. (2019) Cryptococcal Meningitis and Anti-virulence Therapeutic Strategies. Frontiers in Microbiology. 10: 353
Na Pombejra S, Jamklang M, Uhrig JP, et al. (2018) The structure-function analysis of the Mpr1 metalloprotease determinants of activity during migration of fungal cells across the blood-brain barrier. Plos One. 13: e0203020
Vu K, Thompson GR, Roe CC, et al. (2018) Flucytosine resistance in Cryptococcus gattii is indirectly mediated by the FCY2-FCY1-FUR1 pathway. Medical Mycology
Yang ML, Uhrig J, Vu K, et al. (2015) Fluconazole Susceptibility in Cryptococcus gattii is dependent on the ATP binding cassette (ABC) Transporter PDR11. Antimicrobial Agents and Chemotherapy
Vu K, Bautos JM, Gelli A. (2015) The Cch1-Mid1 High-Affinity Calcium Channel Contributes to the Virulence of Cryptococcus neoformans by Mitigating Oxidative Stress. Eukaryotic Cell. 14: 1135-43
Vu K, Tham R, Uhrig JP, et al. (2014) Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. Mbio. 5: e01101-14
Vu K, Eigenheer RA, Phinney BS, et al. (2013) Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cells. Infection and Immunity. 81: 3139-47
Hong MP, Vu K, Bautos JM, et al. (2013) Activity of the calcium channel pore Cch1 is dependent on a modulatory region of the subunit Mid1 in Cryptococcus neoformans. Eukaryotic Cell. 12: 142-50
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