Elizaveta S. Leshchiner, Ph.D.
Affiliations: | 2013 | Chemistry and Chemical Biology | Harvard University, Cambridge, MA, United States |
Area:
General Chemistry, Molecular BiologyGoogle:
"Elizaveta Leshchiner"Mean distance: (not calculated yet)
Parents
Sign in to add mentorLoren D. Walensky | grad student | 2013 | Harvard | |
(Dissecting the mechanisms of direct activation for proapoptotic BAK and BAX.) |
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Publications
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Zou Y, Palte MJ, Deik AA, et al. (2019) A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis. Nature Communications. 10: 1617 |
Leshchiner ES, Rush JS, Durney MA, et al. (2017) Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease. Proceedings of the National Academy of Sciences of the United States of America. 114: 11392-11397 |
Cao Z, Conway KL, Heath RJ, et al. (2015) Ubiquitin Ligase TRIM62 Regulates CARD9-Mediated Anti-fungal Immunity and Intestinal Inflammation. Immunity. 43: 715-26 |
Leshchiner ES, Parkhitko A, Bird GH, et al. (2015) Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proceedings of the National Academy of Sciences of the United States of America. 112: 1761-6 |
Leshchiner ES, Bellairs J, Bird GH, et al. (2014) Abstract B41: Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices Molecular Cancer Research. 12 |
Leshchiner E, Bellairs J, Bird GH, et al. (2014) Abstract 2597: Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices Cancer Research. 74: 2597-2597 |
Hilgendorf KI, Leshchiner ES, Nedelcu S, et al. (2013) The retinoblastoma protein induces apoptosis directly at the mitochondria. Genes & Development. 27: 1003-15 |
Leshchiner ES, Braun CR, Bird GH, et al. (2013) Direct activation of full-length proapoptotic BAK. Proceedings of the National Academy of Sciences of the United States of America. 110: E986-95 |
Gavathiotis E, Reyna DE, Bellairs JA, et al. (2012) Direct and selective small-molecule activation of proapoptotic BAX. Nature Chemical Biology. 8: 639-45 |
Mahon KP, Love KT, Whitehead KA, et al. (2010) Combinatorial approach to determine functional group effects on lipidoid-mediated siRNA delivery. Bioconjugate Chemistry. 21: 1448-54 |