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Evan Q. Comeaux, Ph.D.

Affiliations: 
2013 Pharmacology and Toxicology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
Molecular Biology, Biochemistry
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"Evan Comeaux"
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Robert C. van Waardenburg grad student 2013 UAB
 (structure-function analysis of tyrosyl-DNA phosphodiesterase I.)

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Publications

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Cuya SM, Comeaux EQ, Wanzeck K, et al. (2016) Dysregulated human Tyrosyl-DNA phosphodiesterase I acts as cellular toxin. Oncotarget
Comeaux E, Lin W, Chen T, et al. (2016) PI3K and MEK Inhibition in Hypodiploid Acute Lymphoblastic Leukemia Blood. 128: 1635-1635
Comeaux EQ, Cuya SM, Kojima K, et al. (2015) Tyrosyl-DNA phosphodiesterase I catalytic mutants reveal an alternative nucleophile that can catalyze substrate cleavage. The Journal of Biological Chemistry. 290: 6203-14
Comeaux EQ, van Waardenburg RC. (2014) Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target. Drug Metabolism Reviews. 46: 494-507
Cuya SM, Wanzeck KC, Comeaux EQ, et al. (2013) Abstract 3327: N-terminal domain of Tyrosyl-DNA phosphodiesterase I (Tdp1) is critical for its cellular function. Cancer Research. 73: 3327-3327
Gajewski S, Comeaux EQ, Jafari N, et al. (2012) Analysis of the active-site mechanism of tyrosyl-DNA phosphodiesterase I: a member of the phospholipase D superfamily. Journal of Molecular Biology. 415: 741-58
Comeaux E, Waardenburg Rv, White S, et al. (2012) Abstract 5678: Functional analysis of tyrosyl-DNA phosphodiesterase I catalytic mutants Cancer Research. 72: 5678-5678
Gajewski S, Comeaux EQ, Jafari N, et al. (2012) Corrigendum to “Analysis of the Active-Site Mechanism of Tyrosyl-DNA Phosphodiesterase I: A Member of the Phospholipase D Superfamily” [J. Mol. Biol. 415/4 (2012) 741–758] Journal of Molecular Biology. 416: 725
Comeaux EQ, Gajewski S, Jafaeri N, et al. (2010) Abstract 3645: Functional analysis of tyrosyl-DNA phosphodiesterase 1 catalytic residues Cancer Research. 70: 3645-3645
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