Lavinia C. Dumitrache, Ph.D.
Affiliations: | 2009 | Molecular Medicine | The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States |
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Sign in to add mentorEdward P. Hasty | grad student | 2009 | UT Health San Antonio | |
(Trex2's role in maintaining genomic stability.) |
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Publications
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Kwak YD, Shaw TI, Downing SM, et al. (2021) Chromatin architecture at susceptible gene loci in cerebellar Purkinje cells characterizes DNA damage-induced neurodegeneration. Science Advances. 7: eabg6363 |
Shinoda K, Zong D, Callen E, et al. (2021) The dystonia gene THAP1 controls DNA double-strand break repair choice. Molecular Cell |
Callen E, Zong D, Wu W, et al. (2019) 53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination. Molecular Cell |
Dumitrache LC, Shimada M, Downing SM, et al. (2018) Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors. Proceedings of the National Academy of Sciences of the United States of America |
Enriquez-Rios V, Dumitrache LC, Downing SM, et al. (2017) DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 893-905 |
Enriquez-Rios V, Dumitrache LC, Downing SM, et al. (2016) DNA-PKcs, ATM and ATR interplay maintains genome integrity during neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience |
Shimada M, Dumitrache LC, Russell HR, et al. (2015) Polynucleotide kinase-phosphatase enables neurogenesis via multiple DNA repair pathways to maintain genome stability. The Embo Journal. 34: 2465-80 |
Hu L, Kim TM, Son MY, et al. (2013) Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes. Nature. 501: 569-72 |
Dumitrache LC, Hu L, Son MY, et al. (2011) Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair. Genetics. 188: 787-97 |
Dumitrache LC, Hu L, Hasty P. (2009) TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations. Mutation Research. 662: 84-7 |