Lavinia C. Dumitrache, Ph.D.

Affiliations: 
2009 Molecular Medicine The University of Texas Health Science Center at San Antonio, San Antonio, TX, United States 
Area:
Genetics
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"Lavinia Dumitrache"
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Parents

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Edward P. Hasty grad student 2009 UT Health San Antonio
 (Trex2's role in maintaining genomic stability.)
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Publications

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Hu L, Kim TM, Son MY, et al. (2013) Two replication fork maintenance pathways fuse inverted repeats to rearrange chromosomes. Nature. 501: 569-72
Dumitrache LC, Hu L, Son MY, et al. (2011) Trex2 enables spontaneous sister chromatid exchanges without facilitating DNA double-strand break repair. Genetics. 188: 787-97
Dumitrache LC, Hu L, Hasty P. (2009) TREX2 exonuclease defective cells exhibit double-strand breaks and chromosomal fragments but not Robertsonian translocations. Mutation Research. 662: 84-7
Chen MJ, Dumitrache LC, Wangsa D, et al. (2007) Cisplatin depletes TREX2 and causes Robertsonian translocations as seen in TREX2 knockout cells. Cancer Research. 67: 9077-83
Holcomb VB, Kim TM, Dumitrache LC, et al. (2007) HPRT minigene generates chimeric transcripts as a by-product of gene targeting. Genesis (New York, N.Y. : 2000). 45: 275-81
Chen MJ, Ma SM, Dumitrache LC, et al. (2007) Biochemical and cellular characteristics of the 3' -> 5' exonuclease TREX2. Nucleic Acids Research. 35: 2682-94
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