Daniel M. Mutisya, Ph.D.

Affiliations: 
2014 Chemistry State University of New York at Binghamton, Vestal, NY, United States 
Area:
Organic Chemistry, Biochemistry, Alternative Medicine
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Eriks Rozners grad student 2014 SUNY Binghamton
 (Synthesis, biophysical properties and biological activities of non-ionic RNA analogues having triazole and amide internucleoside linkages.)
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Publications

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Hardcastle T, Novosjolova I, Kotikam V, et al. (2018) A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs. Acs Chemical Biology
Mutisya D, Hardcastle T, Cheruiyot SK, et al. (2017) Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs. Nucleic Acids Research. 45: 8142-8155
Selvam C, Mutisya D, Prakash S, et al. (2017) Therapeutic potential of chemically modified siRNA: Recent trends. Chemical Biology & Drug Design. 90: 665-678
Mutisya D, Selvam C, Lunstad BD, et al. (2014) Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Research. 42: 6542-51
Mutisya D, Selvam C, Kennedy SD, et al. (2011) Synthesis and properties of triazole-linked RNA. Bioorganic & Medicinal Chemistry Letters. 21: 3420-2
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