Elizabeth A. Larimore, Ph.D.

Affiliations: 
2012 Molecular and Cellular Biology University of Washington, Seattle, Seattle, WA 
Area:
Molecular Biology, Biochemistry
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Bruce E. Clurman grad student 2012 University of Washington
 (Dimerization of the Fbw7 ubiquitin ligase impacts substrate regulation, tumor suppressor activity.)
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Publications

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Welcker M, Larimore EA, Swanger J, et al. (2013) Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes & Development. 27: 2531-6
Pierce NW, Lee JE, Liu X, et al. (2013) Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 153: 206-15
Davis MA, Larimore EA, Fissel BM, et al. (2013) The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator. Genes & Development. 27: 151-6
Welcker M, Larimore EA, Frappier L, et al. (2011) Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Molecular and Cellular Biology. 31: 1214-24
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