Stacie Bulfer
Affiliations: | Pharmaceutical Chemistry | University of California, San Francisco, San Francisco, CA |
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LaPorte MG, Burnett JC, Colombo R, et al. (2018) Optimization of Phenyl Indole Inhibitors of the AAA+ ATPase p97. Acs Medicinal Chemistry Letters. 9: 1075-1081 |
Burnett JC, Lim C, Peyser BD, et al. (2017) A threonine turnstile defines a dynamic amphiphilic binding motif in the AAA ATPase p97 allosteric binding site. Organic & Biomolecular Chemistry |
Bulfer SL, Chou TF, Arkin MR. (2016) p97 disease mutations modulate nucleotide-induced con-formation to alter protein-protein interactions. Acs Chemical Biology |
Alverez C, Bulfer SL, Chakrasali R, et al. (2016) Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway. Acs Medicinal Chemistry Letters. 7: 182-7 |
Banerjee S, Bartesaghi A, Merk A, et al. (2016) 2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition. Science (New York, N.Y.) |
Alverez C, Bulfer SL, Chakrasali R, et al. (2016) Allosteric Indole Amide Inhibitors of p97: Identification of a Novel Probe of the Ubiquitin Pathway Acs Medicinal Chemistry Letters. 7: 182-187 |
Alverez C, Arkin MR, Bulfer SL, et al. (2015) Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97. Acs Medicinal Chemistry Letters. 6: 1225-30 |
Zhang X, Gui L, Zhang X, et al. (2015) Altered cofactor regulation with disease-associated p97/VCP mutations. Proceedings of the National Academy of Sciences of the United States of America. 112: E1705-14 |
Chimenti MS, Bulfer SL, Neitz RJ, et al. (2015) A Fragment-Based Ligand Screen Against Part of a Large Protein Machine: The ND1 Domains of the AAA+ ATPase p97/VCP. Journal of Biomolecular Screening. 20: 788-800 |
Alverez C, Arkin MR, Bulfer SL, et al. (2015) Structure-Activity Study of Bioisosteric Trifluoromethyl and Pentafluorosulfanyl Indole Inhibitors of the AAA ATPase p97 Acs Medicinal Chemistry Letters. 6: 1225-1230 |