Nicholas Sylvain, Ph.D.
|2011||Immunology||Sackler School of Graduate Biomedical Sciences (Tufts University)|
Area:Immunology, Cell Biology
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|Stephen C. Bunnell||grad student||2011||Sackler School of Graduate Biomedical Sciences (Tufts University)|
|(Vav1 Controls the Stability and Function of SLP-76 Containing Signaling Microclusters.)|
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|Fray MA, Charpentier JC, Sylvain NR, et al. (2020) Vav2 lacks calcium entry-promoting scaffolding functions unique to Vav1 and inhibits T cell activation via Cdc42. Journal of Cell Science|
|Sylvain NR, Nguyen K, Bunnell SC. (2011) Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses. Science Signaling. 4: ra14|
|Nguyen K, Sylvain NR, Bunnell SC. (2008) T cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76. Immunity. 28: 810-21|