Artem G. Lada, Ph.D.

Affiliations: 
2014 University of Nebraska Medical Center, Omaha, NE, United States 
Area:
Molecular Biology, Genetics, Biochemistry
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"Artem Lada"
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Parents

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Youri I. Pavlov grad student 2014 University of Nebraska Medical Center
 (Mechanisms of regulation of AID/APOBEC deaminases activity and protection of the genome from promiscuous deamination.)
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Publications

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Zhuk AS, Lada AG, Pavlov YI. (2023) Polymorphism of Strains in DNA Metabolism Genes. International Journal of Molecular Sciences. 24
Aksenova AY, Zhuk AS, Lada AG, et al. (2021) Genome Instability in Multiple Myeloma: Facts and Factors. Cancers. 13
Rogozin IB, Roche-Lima A, Tyryshkin K, et al. (2021) DNA Methylation, Deamination, and Translesion Synthesis Combine to Generate Footprint Mutations in Cancer Driver Genes in B-Cell Derived Lymphomas and Other Cancers. Frontiers in Genetics. 12: 671866
Stepchenkova EI, Zhuk AS, Cui J, et al. (2021) Compensation for the absence of the catalytically active half of DNA polymerase ε in yeast by positively selected mutations in CDC28. Genetics
Rogozin IB, Roche-Lima A, Lada AG, et al. (2019) Nucleotide Weight Matrices Reveal Ubiquitous Mutational Footprints of AID/APOBEC Deaminases in Human Cancer Genomes. Cancers. 11
Lada AG, Stepchenkova EI, Zhuk AS, et al. (2017) Recombination Is Responsible for the Increased Recovery of Drug-Resistant Mutants with Hypermutated Genomes in Resting Yeast Diploids Expressing APOBEC Deaminases. Frontiers in Genetics. 8: 202
Rogozin IB, Goncearenco A, Lada AG, et al. (2017) DNA polymerase η mutational signatures are found in a variety of different types of cancer. Cell Cycle (Georgetown, Tex.). 1-31
Rogozin IB, Pavlov YI, Goncearenco A, et al. (2017) Mutational signatures and mutable motifs in cancer genomes. Briefings in Bioinformatics
Rogozin IB, Lada AG, Goncearenco A, et al. (2016) Activation induced deaminase mutational signature overlaps with CpG methylation sites in follicular lymphoma and other cancers. Scientific Reports. 6: 38133
Lada AG, Kliver SF, Dhar A, et al. (2015) Disruption of Transcriptional Coactivator Sub1 Leads to Genome-Wide Re-distribution of Clustered Mutations Induced by APOBEC in Active Yeast Genes. Plos Genetics. 11: e1005217
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