Christopher J. Mingone, Ph.D.

Affiliations: 
2005 New York Medical College, New York, NY, United States 
Area:
Physiology Biology
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Michael S. Wolin grad student 2005 New York Medical College
 (Mechanisms Regulating Nitric Oxide-mediated Vascular Relaxation through Soluble Guanylate Cyclase by Hypoxia, Thiol Redox and Heme Metabolism.)
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Publications

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Wolin MS, Gupte SA, Mingone CJ, et al. (2010) Redox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiology. Annals of the New York Academy of Sciences. 1203: 126-32
Mingone CJ, Ahmad M, Gupte SA, et al. (2008) Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1244-50
Mingone CJ, Gupte SA, Chow JL, et al. (2006) Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L337-44
Mingone CJ, Gupte SA, Ali N, et al. (2006) Thiol oxidation inhibits nitric oxide-mediated pulmonary artery relaxation and guanylate cyclase stimulation. American Journal of Physiology. Lung Cellular and Molecular Physiology. 290: L549-57
Ahmad M, Turkseven S, Mingone CJ, et al. (2005) Heme oxygenase-1 gene expression increases vascular relaxation and decreases inducible nitric oxide synthase in diabetic rats. Cellular and Molecular Biology (Noisy-Le-Grand, France). 51: 371-6
Turkseven S, Kruger A, Mingone CJ, et al. (2005) Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes. American Journal of Physiology. Heart and Circulatory Physiology. 289: H701-7
Mingone CJ, Gupte SA, Quan S, et al. (2003) Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP. Experimental Biology and Medicine (Maywood, N.J.). 228: 535-9
Mingone CJ, Gupte SA, Iesaki T, et al. (2003) Hypoxia enhances a cGMP-independent nitric oxide relaxing mechanism in pulmonary arteries. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L296-304
Abraham NG, Quan S, Mieyal PA, et al. (2002) Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L1117-24
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