Benjamin N. Combs, Ph.D.

Affiliations: 
2013 Molecular Biosciences University of Kansas, Lawrence, KS, United States 
Area:
Molecular Biology, Biochemistry
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Parents

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Truman C. Gamblin grad student 2013 University of Kansas
 (Modifications of the tau protein and their varied effects on aggregation and function.)
Nicholas M Kanaan post-doc 2012-2017 Michigan State (Neurotree)
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Publications

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Mueller RL, Kanaan NM, Combs B. (2023) Using Live-Cell Imaging to Measure the Effects of Pathological Proteins on Axonal Transport in Primary Hippocampal Neurons. Journal of Visualized Experiments : Jove
Christensen KR, Combs B, Richards C, et al. (2023) Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons. Molecular Neurobiology
Aquino Nunez W, Combs B, Gamblin TC, et al. (2022) Age-dependent accumulation of tau aggregation in . Frontiers in Aging. 3: 928574
Combs B, Christensen KR, Richards C, et al. (2021) FTLD mutant tau impairs axonal transport through a protein phosphatase 1γ-dependent mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Mueller RL, Combs B, Alhadidy MM, et al. (2021) Tau: A Signaling Hub Protein. Frontiers in Molecular Neuroscience. 14: 647054
Kanaan NM, Hamel C, Grabinski T, et al. (2020) Liquid-liquid phase separation induces pathogenic tau conformations in vitro. Nature Communications. 11: 2809
Combs B, Mueller RL, Morfini G, et al. (2019) Tau and Axonal Transport Misregulation in Tauopathies. Advances in Experimental Medicine and Biology. 1184: 81-95
Mutreja Y, Combs B, Gamblin TC. (2019) FTDP-17 Mutations Alter the Aggregation and Microtubule Stabilization Propensity of Tau in an Isoform-Specific Fashion Biochemistry. 58: 742-754
Kneynsberg A, Combs B, Christensen K, et al. (2017) Axonal Degeneration in Tauopathies: Disease Relevance and Underlying Mechanisms. Frontiers in Neuroscience. 11: 572
Combs B, Tiernan CT, Hamel C, et al. (2017) Production of recombinant tau oligomers in vitro. Methods in Cell Biology. 141: 45-64
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