Patrick T. Gunning

Chemistry University of Toronto, Toronto, ON, Canada 
Molecular Chemistry, Cell Biology, Oncology
"Patrick Gunning"
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Murcar-Evans BI, Cabral AD, Toutah K, et al. (2017) ProxyPhos sensors for the detection of negatively charged membranes. The Analyst
Cabral AD, Murcar-Evans BI, Toutah K, et al. (2017) Structure-activity relationship study of ProxyPhos chemosensors for the detection of proximal phosphorylation and other phosphate species. The Analyst
Kraskouskaya D, Cabral AD, Fong R, et al. (2017) Characterization and application studies of ProxyPhos, a chemosensor for the detection of proximally phosphorylated peptides and proteins in aqueous solutions. The Analyst
Eiring AM, Page BDG, Kraft IL, et al. (2017) Combined STAT3 and BCR-ABL1 inhibition induces synthetic lethality in therapy-resistant chronic myeloid leukemia. Leukemia. 31: 1253-1254
Linher-Melville K, Nashed M, Ungard R, et al. (2017) Abstract P3-03-13: Chronic inhibition of signal transducer and activator of transcription 3/5 in treatment-resistant human breast cancer cell subtypes: Convergence on the reactive oxyten species/SUMOylation pathway and its effects on xCT expression and system xc-activity Cancer Research. 77
de Araujo ED, Geletu M, Gunning PT. (2016) Strategies for over-expression and purification of recombinant full length STAT5B in Escherichia coli. Protein Expression and Purification
Linher-Melville K, Nashed MG, Ungard RG, et al. (2016) Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity. Plos One. 11: e0161202
Wilson AJ, Gunning PT. (2016) Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 2). Chemmedchem
Ali AM, Gómez-Biagi RF, Rosa DA, et al. (2016) Disarming an Electrophilic Warhead: Retaining Potency in Tyrosine Kinase Inhibitor (TKI)-Resistant CML Lines While Circumventing Pharmacokinetic Liabilities. Chemmedchem
Wilson AJ, Gunning PT. (2016) Understanding Protein-Protein Interactions: Essential Players in (Patho)physiology (Part 1). Chembiochem : a European Journal of Chemical Biology
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