Christine Bear
Affiliations: | Biochemistry | University of Toronto, Toronto, ON, Canada |
Area:
Cell Biology, Physiology Biology, Pharmacology, BiochemistryGoogle:
"Christine Bear"Mean distance: (not calculated yet)
Children
Sign in to add trainee| Katalin Gyomorey | grad student | 2000 | University of Toronto |
| Ilana Kogan | grad student | 2003 | University of Toronto |
| Stanislav P. Pasyk | grad student | 2014 | University of Toronto |
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Publications
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| Birimberg-Schwartz L, Ip W, Bartlett C, et al. (2023) Validating organoid-derived human intestinal monolayers for personalized therapy in cystic fibrosis. Life Science Alliance. 6 |
| Xia S, Di Paola M, Jones NL, et al. (2022) A Fluorescence-based Assay of Membrane Potential for High-throughput Functional Study of Two Endogenous Ion Channels in Two Epithelial Cell Lines. Journal of Visualized Experiments : Jove |
| Lim SH, Snider J, Birimberg-Schwartz L, et al. (2022) CFTR interactome mapping using the mammalian membrane two-hybrid high-throughput screening system. Molecular Systems Biology. 18: e10629 |
| Xia S, Bozóky Z, Di Paola M, et al. (2021) High-Throughput Functional Analysis of CFTR and Other Apically Localized Proteins in iPSC-Derived Human Intestinal Organoids. Cells. 10 |
| Derichs N, Taylor-Cousar JL, Davies JC, et al. (2021) Riociguat for the treatment of Phe508del homozygous adults with cystic fibrosis. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society |
| Laselva O, Qureshi Z, Zeng ZW, et al. (2021) Identification of binding sites for ivacaftor on the cystic fibrosis transmembrane conductance regulator. Iscience. 24: 102542 |
| Laselva O, Ardelean MC, Bear CE. (2021) Phenotyping Rare CFTR Mutations Reveal Functional Expression Defects Restored by TRIKAFTA. Journal of Personalized Medicine. 11 |
| Laselva O, McCormack J, Bartlett C, et al. (2020) Preclinical Studies of a Rare CF-Causing Mutation in the Second Nucleotide Binding Domain (c.3700A>G) Show Robust Functional Rescue in Primary Nasal Cultures by Novel CFTR Modulators. Journal of Personalized Medicine. 10 |
| Laselva O, Bartlett C, Popa A, et al. (2020) Emerging preclinical modulators developed for F508del-CFTR have the potential to be effective for ORKAMBI resistant processing mutants. Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society |
| Erwood S, Laselva O, Bily TMI, et al. (2020) Allele-Specific Prevention of Nonsense-Mediated Decay in Cystic Fibrosis Using Homology-Independent Genome Editing. Molecular Therapy. Methods & Clinical Development. 17: 1118-1128 |