Jurgen Sygusch

Affiliations: 
Faculte de medecine Université de Montréal, Montréal, Canada 
Area:
Molecular Biology, Biochemistry
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"Jurgen Sygusch"
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Publications

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Belardinelli JM, Yazidi A, Yang L, et al. (2016) Structure-Function Profile of MmpL3, the Essential Mycolic Acid Transporter from Mycobacterium tuberculosis. Acs Infectious Diseases. 2: 702-713
Wahba H, Lecoq L, Stevenson MJ, et al. (2016) Structural and biochemical characterization of a copper-binding mutant of the organomercurial lyase MerB: Insight into the key role of the active site aspartic acid in both Hg-carbon bond cleavage and metal-binding specificity. Biochemistry
Tanner JE, Coinçon M, Leblond V, et al. (2015) Peptides designed to spatially depict the Epstein-Barr virus major virion glycoprotein gp350 neutralization epitope elicit antibodies that block virus-neutralizing antibody 72A1 interaction with the native gp350 molecule. Journal of Virology. 89: 4932-41
Cappadocia L, Parent JS, Sygusch J, et al. (2013) A family portrait: structural comparison of the Whirly proteins from Arabidopsis thaliana and Solanum tuberosum. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1207-11
Smith MA, Coinçon M, Paschos A, et al. (2012) Identification of the binding site of Brucella VirB8 interaction inhibitors. Chemistry & Biology. 19: 1041-8
Coincon M, Wang W, Sygusch J, et al. (2012) Crystal structure of reaction intermediates in pyruvate class II aldolase: substrate cleavage, enolate stabilization, and substrate specificity. The Journal of Biological Chemistry. 287: 36208-21
Cappadocia L, Parent JS, Zampini E, et al. (2012) A conserved lysine residue of plant Whirly proteins is necessary for higher order protein assembly and protection against DNA damage. Nucleic Acids Research. 40: 258-69
Mabiala-Bassiloua CG, Arthus-Cartier G, Hannaert V, et al. (2011) Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases. Acs Medicinal Chemistry Letters. 2: 804-8
de la Paz Santangelo M, Gest PM, Guerin ME, et al. (2011) Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli. The Journal of Biological Chemistry. 286: 40219-31
Daher R, Coinçon M, Fonvielle M, et al. (2010) Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases. Journal of Medicinal Chemistry. 53: 7836-42
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