Vijay M. Shahani, Ph.D.

Affiliations: 
2013 Chemistry University of Toronto, Toronto, ON, Canada 
Area:
Molecular Chemistry, Cell Biology, Oncology
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"Vijay Shahani"
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Parents

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Patrick T. Gunning grad student 2013 University of Toronto
 (An Exploration into the Molecular Recognition of Signal Transducer and Activator of Transcription 3 Protein Via Rationally Designed Small Molecule Binders.)
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Publications

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Shahani VM, Yue P, Haftchenary S, et al. (2023) Retraction of "Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies". Acs Medicinal Chemistry Letters. 14: 1482
Martic S, Rains MK, Haftchenary S, et al. (2014) Electrochemical detection of the Fc-STAT3 phosphorylation and STAT3-Fc-STAT3 dimerization and inhibition. Molecular Biosystems. 10: 576-80
Haftchenary S, Luchman HA, Jouk AO, et al. (2013) Potent Targeting of the STAT3 Protein in Brain Cancer Stem Cells: A Promising Route for Treating Glioblastoma. Acs Medicinal Chemistry Letters. 4: 1102-7
Shahani VM, Ball DP, Ramos AV, et al. (2013) A 2,6,9-hetero-trisubstituted purine inhibitor exhibits potent biological effects against multiple myeloma cells. Bioorganic & Medicinal Chemistry. 21: 5618-28
Haftchenary S, Ball DP, Aubry I, et al. (2013) Identification of a potent salicylic acid-based inhibitor of tyrosine phosphatase PTP1B Medchemcomm. 4: 987-992
Lukkarila JL, da Silva SR, Ali M, et al. (2011) Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity. Acs Medicinal Chemistry Letters. 2: 577-82
Shahani VM, Yue P, Haftchenary S, et al. (2011) Identification of Purine-Scaffold Small-Molecule Inhibitors of Stat3 Activation by QSAR Studies. Acs Medicinal Chemistry Letters. 2: 79-84
Shahani VM, Yue P, Fletcher S, et al. (2011) Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein. Bioorganic & Medicinal Chemistry. 19: 1823-38
Fletcher S, Shahani VM, Lough AJ, et al. (2010) Concise access to N9-mono-, N2-mono- and N2,N9-di-substituted guanines via efficient Mitsunobu reactions Tetrahedron. 66: 4621-4632
Fletcher S, Drewry JA, Shahani VM, et al. (2009) Molecular disruption of oncogenic signal transducer and activator of transcription 3 (STAT3) protein. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 87: 825-33
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