Jean Buteau, Ph.D.

Affiliations: 
2004 Université de Montréal, Montréal, Canada 
Area:
Molecular Biology
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"Jean Buteau"
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Marc Prentki grad student 2004 Université de Montréal
 (Le glucagon -like peptide -1: Un facteur de croissance et une hormone anti-apoptotique pour la cellule pancreatique beta. Etude de la transduction du signal.)
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Publications

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Lin H, Smith N, Spigelman AF, et al. (2021) β-Cell Knockout of SENP1 Reduces Responses to Incretins and Worsens Oral Glucose Tolerance in High Fat Diet-Fed Mice. Diabetes
Close AF, Dadheech N, Lemieux H, et al. (2020) Disruption of Beta-Cell Mitochondrial Networks by the Orphan Nuclear Receptor Nor1/Nr4a3. Cells. 9
Close AF, Dadheech N, Villela BS, et al. (2019) The Orphan Nuclear Receptor Nor1/Nr4a3 Is a Negative Regulator of β-Cell Mass. The Journal of Biological Chemistry
Dadheech N, Garrel D, Buteau J. (2018) Evidence of unrestrained beta-cell proliferation and neogenesis in a patient with hyperinsulinemic hypoglycemia after gastric bypass surgery. Islets. 1-8
Purwana I, Liu JJ, Portha B, et al. (2017) HSF1 acetylation decreases its transcriptional activity and enhances glucolipotoxicity-induced apoptosis in rat and human beta cells. Diabetologia
Henry C, Close AF, Buteau J. (2014) A critical role for the neural zinc factor ST18 in pancreatic β-cell apoptosis. The Journal of Biological Chemistry. 289: 8413-9
Paradis R, Lazar N, Antinozzi P, et al. (2013) Nov/Ccn3, a novel transcriptional target of FoxO1, impairs pancreatic β-cell function. Plos One. 8: e64957
Talbot J, Joly E, Prentki M, et al. (2012) β-Arrestin1-mediated recruitment of c-Src underlies the proliferative action of glucagon-like peptide-1 in pancreatic β INS832/13 cells. Molecular and Cellular Endocrinology. 364: 65-70
Bastien-Dionne PO, Valenti L, Kon N, et al. (2011) Glucagon-like peptide 1 inhibits the sirtuin deacetylase SirT1 to stimulate pancreatic β-cell mass expansion. Diabetes. 60: 3217-22
Buteau J. (2011) GLP-1 signaling and the regulation of pancreatic β-cells mass/function Avances En Diabetologia. 27: 3-8
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