Julien Lamontagne, Ph.D.

Affiliations: 
2012 Biochemistry Université de Montréal, Montréal, Canada 
Area:
Animal Physiology Biology, Pharmaceutical Chemistry, Cell Biology, Medicine and Surgery
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Parents

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Marc Prentki grad student 2012 Université de Montréal
 (Effets directs et aigus de medicaments insulinosensibilisateurs sur la cellule beta des ilots pancreatiques : de l'outil de recherche a l'identification de la deceleration metabolique comme mode d'action.)
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Publications

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Lamontagne J, Al-Mass A, Nolan CJ, et al. (2017) Identification of the signals for glucose-induced insulin secretion in INS1 (832/13) β-cells using metformin-induced metabolic deceleration as a model. The Journal of Biological Chemistry
Mugabo Y, Zhao S, Lamontagne J, et al. (2017) Metabolic fate of glucose and candidate signaling and excess-fuel detoxification pathways in pancreatic β-cells. The Journal of Biological Chemistry
Pepin É, Al-Mass A, Attané C, et al. (2016) Pancreatic β-Cell Dysfunction in Diet-Induced Obese Mice: Roles of AMP-Kinase, Protein Kinase Cε, Mitochondrial and Cholesterol Metabolism, and Alterations in Gene Expression. Plos One. 11: e0153017
Mugabo Y, Zhao S, Seifried A, et al. (2016) Identification of a mammalian glycerol-3-phosphate phosphatase: Role in metabolism and signaling in pancreatic β-cells and hepatocytes. Proceedings of the National Academy of Sciences of the United States of America
Iglesias J, Lamontagne J, Erb H, et al. (2015) Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of of known inhibitors. Journal of Lipid Research
Lamontagne J, Jalbert-Arsenault E, Pepin E, et al. (2013) Pioglitazone acutely reduces energy metabolism and insulin secretion in rats. Diabetes. 62: 2122-9
Delghingaro-Augusto V, Décary S, Peyot ML, et al. (2012) Voluntary running exercise prevents β-cell failure in susceptible islets of the Zucker diabetic fatty rat. American Journal of Physiology. Endocrinology and Metabolism. 302: E254-64
Peyot ML, Pepin E, Lamontagne J, et al. (2010) Beta-cell failure in diet-induced obese mice stratified according to body weight gain: secretory dysfunction and altered islet lipid metabolism without steatosis or reduced beta-cell mass. Diabetes. 59: 2178-87
Peyot ML, Gray JP, Lamontagne J, et al. (2009) Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. Plos One. 4: e6221
Lamontagne J, Pepin E, Peyot ML, et al. (2009) Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations. Endocrinology. 150: 3465-74
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