Bik-Kwoon Tye

Cornell University, Ithaca, NY, United States 
Biochemistry, Molecular Biology
"Bik-Kwoon Tye"

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David Botstein grad student 1974 MIT
 (Chromosome Structure and DNA Encapsulation in Phage P22)


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Nancy L. Douglas grad student 2003 Cornell
Chanmi Lee grad student 2009 Cornell
Judith Berman post-doc Cornell
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Li J, Dong J, Wang W, et al. (2023) The human pre-replication complex is an open complex. Cell. 186: 98-111.e21
Li N, Lam WH, Zhai Y, et al. (2018) Structure of the origin recognition complex bound to DNA replication origin. Nature
Li N, Zhai Y, Zhang Y, et al. (2015) Structure of the eukaryotic MCM complex at 3.8 Å. Nature. 524: 186-91
Liu C, Wu R, Zhou B, et al. (2012) Structural insights into the Cdt1-mediated MCM2-7 chromatin loading. Nucleic Acids Research. 40: 3208-17
Liachko I, Tanaka E, Cox K, et al. (2011) Novel features of ARS selection in budding yeast Lachancea kluyveri. Bmc Genomics. 12: 633
Tye BK. (2010) Old-fashioned genetic screens give new insights to DNA replication. Cell Cycle (Georgetown, Tex.). 9: 4610-1
Liachko I, Bhaskar A, Lee C, et al. (2010) A comprehensive genome-wide map of autonomously replicating sequences in a naive genome. Plos Genetics. 6: e1000946
Lee C, Liachko I, Bouten R, et al. (2010) Alternative mechanisms for coordinating polymerase alpha and MCM helicase. Molecular and Cellular Biology. 30: 423-35
Eisenberg S, Korza G, Carson J, et al. (2009) Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 25412-20
Liachko I, Tye BK. (2009) Mcm10 mediates the interaction between DNA replication and silencing machineries Genetics. 181: 379-391
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