Horrick Sharma, Ph.D.

Affiliations: 
2011 Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmacy
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John K. Buolamwini grad student 2011 UTHSC
 (Synthesis and computational studies on HIV-1 integrase inhibitors.)
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Publications

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Sharma H. (2018) Targeting Cancer Metabolism as a Novel Anticancer Strategy. Current Topics in Medicinal Chemistry. 18: 429-431
Wei C, Bajpai R, Sharma H, et al. (2017) Development of GLUT4-selective antagonists for multiple myeloma therapy. European Journal of Medicinal Chemistry. 139: 573-586
Santra S, Sharma H, Vedachalam S, et al. (2015) Development of potent dopamine-norepinephrine uptake inhibitors (DNRIs) based on a (2S,4R,5R)-2-benzhydryl-5-((4-methoxybenzyl)amino)tetrahydro-2H-pyran-4-ol molecular template. Bioorganic & Medicinal Chemistry. 23: 821-8
Nag S, Qin JJ, Voruganti S, et al. (2015) Development and validation of a rapid HPLC method for quantitation of SP-141, a novel pyrido[b]indole anticancer agent, and an initial pharmacokinetic study in mice. Biomedical Chromatography : Bmc. 29: 654-63
Dutta AK, Santra S, Sharma H, et al. (2014) Pharmacological and behavioral characterization of D-473, an orally active triple reuptake inhibitor targeting dopamine, serotonin and norepinephrine transporters. Plos One. 9: e113420
Wang W, Qin JJ, Voruganti S, et al. (2014) The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models. Nature Communications. 5: 5086
Wang W, Qin JJ, Voruganti S, et al. (2014) Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice. Gastroenterology. 147: 893-902.e2
Sharma H, Santra S, Debnath J, et al. (2014) Flexible and biomimetic analogs of triple uptake inhibitor 4-((((3S,6S)-6-benzhydryltetrahydro-2H-pyran-3-yl)amino)methyl)phenol: Synthesis, biological characterization, and development of a pharmacophore model. Bioorganic & Medicinal Chemistry. 22: 311-24
dutta a, Sharma H, Santra S, et al. (2014) Development of Pharmacophore Model and Asymmetric Synthesis of Novel Tetrahydrofuran Derivatives Enroute to Triple Uptake Inhibitors As Anti-Depressant Agents Scienceopen Posters
Sharma H, Sanchez TW, Neamati N, et al. (2013) Synthesis, docking, and biological studies of phenanthrene β-diketo acids as novel HIV-1 integrase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6146-51
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